Pathogenesis and pathogenicity for the porcine circovirus 2 Korean isolates in weaned pigs
2007
Roh, I.S. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Lee, K.W. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Kim, J.H. (Cheju National University, Jeju, Republic of Korea) | Han, J.H. (Kangwon National University, Chuncheon, Republic of Korea) | Jean, Y.H. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea), E-mail: jean@nvrqs.go.kr
This study was carried out to investigate the pathogenesis and pathogenicity of the porcine circovirus type 2 (PCV2) Korean isolate from weaned pigs. Twenty four weaned pigs, PCV2, porcine reproductive and respiratory syndrome virus (PRRSV) and porcine parvovirus (PPV) antibodies free, were allocated to 4 groups (n=6). Six pigs were inoculated intranasally with PCV2 alone, 6 with PCV2 and PRRSV, 6 with the combined PCV2/PRRSV/PPV inoculum, and 6 were remained as a uninoculated negative control. Pigs were killed 3 and 6 weeks after inoculation and tissue samples examined for gross and microscopic lesions and for the presence of PCV2 antigens and nucleic acids.
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