Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity

M. RamÃƒÂ­rez-Osuna; D. ChÃƒÂ¡vez; L. HernÃƒÂ¡ndez; E. Molins; R. Somanathan; G. Aguirre

Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity

2005

Syntheses of three non-brominated analogs of amathamide A (1), a natural alkaloid isolated from the Tasmanian marine bryozoan Amathia wilsoni, are described. Antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomona aeruginosa, and Candida albicans was tested. Test results for amathamide A (1) showed a weak activity against C. albicans and E. coli. The three non-natural analogs 2-4 proved to be inactive compounds.

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Издатель

Molecular Diversity Preservation International

Другие темы

Antimicrobial activity.; Organic synthesis; Amathamide a

Язык

Английский

В АГРИСе с: 2013-06-15

Формат: AGRIS AP

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Эту запись предоставил AVANO

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Ссылки

http://www.doaj.org/doaj?func=openurl&genre=article&issn=14203049&date=2005&volume=10&issue=1&spage=295 http://www.mdpi.com/1420-3049/10/1/295/

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Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity

2005

Библиографическая информация