Formaldehyde Content in the Rui Fish (Labeo rohita) in Bangladesh and Effect of Formaldehyde on Lipid Peroxidation in Rat Liver and Intestinal Tissues
2008
Md. Shahdat Hossain | Mohammad Azizur Rahman | Tofael Kabir Sharkar | Hussain Md. Shahjalal
This study was conducted to estimate formaldehyde levels in the rui fish (Labeo rohita) in Bangladesh. Results showed that formaldehyde levels were significantly higher in the imported rui fish than that of the fresh rui of local ponds [mean levels: 13.40 ±0.52 vs. 3.95 ±0.40 (nmol mg–<SUP>1</SUP> of fish protein)]. The effect of formaldehyde on lipid peroxidation was also examined and found a significantly higher lipid peroxide levels in the liver and the intestinal tissues of the orally formaldehyde-administered rats (4.8 and 3.7 folds, respectively) than those of the control rats. A dose dependent increase of lipid peroxide value also was observed in rat liver and intestinal epithelial cell homogenates, when these were in vitro treated with different concentration of formaldehyde (0~500 μM). These results suggest that formaldehyde has considerable tissue damaging effects; thus formaldehyde consumption through fomalinated-fish should be avoided.
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