Chemical Constituents from Euphorbia kansui

Qiao Zhang; Qin-Rong Zhou; Jian-Wei Lou; Pei-Dong Chen; Wei-Feng Yao; Wei-Wei Tao; Yu-Ping Tang; Guan-Cheng Dai; Kun Wang; Li Zhang

Chemical Constituents from Euphorbia kansui

In this research, a new triterpenoid, tirucalla-8,24-diene-3β,11β-diol-7-one (1), and eupha-8,24-diene-3β,11β-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3–14), were isolated from the ethyl acetate extract of Euphorbia kansui. Their structures were elucidated based on High resolution electrospray ionization mass spectrometry (HR-ESI-MS), Infrared Spectroscopy (IR), 1D and 2D Nuclear Magnetic Resonance (NMR) data. Both constituents 1 and 2 exhibited moderate cytotoxicity against colon cancer HCT-116, gastric cancer MKN-45 and breast cancer MCF-7.

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