Chemical composition and antimicrobial activity of Satureja, Thymus, and Thymbra species grown in Lebanon

Al Hafi, Monay; El Beyrouthy, Marc; Ouaini, Naim,; Stien, Didier; Rutledge, Douglas; Chaillou, Sylvain,

Chemical composition and antimicrobial activity of Satureja, Thymus, and Thymbra species grown in Lebanon

2017

The essential oils were extracted by hydrodistillation from Satureja cuneifolia, Satureja thymbra, Coridothymus capitatus, Thymus syriacus, and Thymbra spicata growing wild in Lebanon. Their phytochemical analysis performed by GC/MS showed that the aforementioned species are characterized either by carvacrol (60.9%) or thymol (54.3%) or by a more or less equal amounts of these two phenols. Assessment of their in vitro antimicrobial activity against Candida albicans and six pathogenic bacteria using the broth dilution method revealed that the tested oils have a broad activity spectrum with minimum inhibitory concentration ranging from 0.1 to 0.8 mg/ml. Among the tested species, S. thymbra EO showed the highest antimicrobial potential whereas T. syriacus showed the lowest inhibitory activity. These results give scientific evidence for the use of those species in the Lebanese folk medicine and lend support to implement them as natural alternatives for synthetic antimicrobials.

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