Inhaled Colistin Usage in the Treatment of Health-Care Associated Pneumoniae Due to Multi-Drug Resistant Gram-Negative Microorganism

Gül Ruhsar YILMAZ; Tümer GÜVEN

Inhaled Colistin Usage in the Treatment of Health-Care Associated Pneumoniae Due to Multi-Drug Resistant Gram-Negative Microorganism

2013

Gül Ruhsar YILMAZ | Tümer GÜVEN

Hospital-acquired pneumoniae and ventilatory-associated pneumoniae (VAP) were the most common health-care associated infections leading to high mortality rates. Intravenous colistin which is used for infections due to multi-drug resistant microorganisms has poor penetration into the lung. Inhaled colistin usage seems promising in the treatment of the VAP causing high mortality. The results of the studies regarding clinical efficacy of colistin were controversial. Inhaled colistin usage in the treatment of VAP was reviewed according to the literature.

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