Successful transfer of DHP-degrading bacteria from Hawaiian goats to Australian ruminants to overcome the toxicity of Leucaena [3-hydroxy-4(1H)-pyridone]
1986
Jones, R.J. | Megarrity, R.G. (Commonwealth Scientific and Industrial Research Organization, Aitkenvale (Australia). Div. of Tropical Crops and Pastures)
A mixed bacterial population capable of rapidly degrading DHP in vitro without added sugars was isolated from a goat on Maui; cultures were introduced at Townsville and multiplied in isolation. Infusion of the culture into a goat and a steer fed solely on leucaena resulted in cessation of DHP excretion in the urine. After 60 days, the serum thyroxine levels and thyroid size were normal and there were no clinical signs of disease. The rumen fluid degraded DHP in vitro 58 days after infusion.
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