Chemical constituents from Lindera nacusua (D. Don) Merr

Wei, Guo-Qing; Zhang, Jia-Sui; Lei, Jie-Ping; Ma, Chao-Ying; Tong, Yan; Jiang, He-Zhong

Chemical constituents from Lindera nacusua (D. Don) Merr

2016

This first phytochemical investigation on the roots of Lindera nacusua (D. Don) Merr led to the isolation of nine compounds, including demethylmacrosporine I (1), emodin-6-O-β-D-gluco- pyranoside (2), (−)-litsenolide D1 (3), (−)-(2Z,3R,4S)-2-(dodec-11-ynylidene)-3-hydroxy-4-methyilbu- tanolide (4), 1-O-3,4-dimethoxy-5-hydroxyphenyl-(6-O-3,5-dimethoxygalloyl)-β-d-glucopyranoside (5), 1-O-3,4-dimethoxy-5-hydroxyphenyl-(6-O-va-nilloyl)-β-d-glucopyranoside (6), (E)-feruloyltyra- mine (7), Z-N-feruloyltyramine (8), and 1-O-β-d-glucopyranosyl-(2S,3R,4E,8Z)-2-[2’(R)-hydroxyhex- adecanoyl-amino]-4,8-octadecadiene-1,3-diol (9). The types of the compounds involved anthraquinones (1, 2), γ-butanolides (3, 4), phenolic glycosides (5, 6), phenolic acid amides (7, 8) and cerebroside (9). Among them, Compounds 1–6 and 9 were firstly isolated from the genus Lindera as well as the Lauraceae family, and the anthraquinones and cerebrosides were first found in the Lauraceae family. The chemotaxonomic significance of these compounds was also summarized.

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