Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi)

Zaugg, J.L.; Lane, V.M.

Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi)

1989

Zaugg, J.L. | Lane, V.M.

We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.

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