The complete genome sequence of the lumpy skin disease virus vaccine Herbivac LS reveals a mutation in the superoxide dismutase gene homolog

Douglass, Nicola; Van Der Walt, Anelda; Omar, Ruzaiq; Munyanduki, Henry; Williamson, Anna-Lise

The complete genome sequence of the lumpy skin disease virus vaccine Herbivac LS reveals a mutation in the superoxide dismutase gene homolog

2019

Douglass, Nicola | Van Der Walt, Anelda | Omar, Ruzaiq | Munyanduki, Henry | Williamson, Anna-Lise

The lumpy skin disease virus (LSDV) vaccine, Herbivac LS, batch 008, was sequenced and found to differ from the Neethling vaccine strain in the locus encoding a superoxide dismutase (SOD) homolog. The presence of a SOD homolog, be it full-length (as in Herbivac LS) or truncated (as in Neethling) may affect vaccine immunogenicity.

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