Impact of oral gut decontamination on Staphylococcus aureus colonisation in patients undergoing allogeneic haematopoietic stem cell transplantation
2017
Wilk, C Matthias | Weber, Isabel | Seidl, Kati | Rachmühl, Carole | Holzmann-Bürgel, Anne | Müller, Antonia M.S. | Kuster, Stefan P. | Schanz, Urs | Zinkernagel, Annelies S.
Recipients of allogeneic haematopoietic stem cell transplantation (allo-HSCT) are severely immunocompromised and are at increased risk of infection. In this prospective, observational, single-centre study including 110 allo-HSCT recipients, the rate of Staphylococcus aureus colonisation was reduced from 11.8% to 0% (P < 0.001) following peritransplant oral gut decontamination. No invasive S. aureus infections were observed.
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