Phenolic compounds from the flowers of Nepalese medicinal plant Aconogonon molle and their DPPH free radical-scavenging activities

Joshi, Khem Raj; Devkota, Hari Prasad; Watanabe, Takashi; Yahara, Shōji

Phenolic compounds from the flowers of Nepalese medicinal plant Aconogonon molle and their DPPH free radical-scavenging activities

2014

Joshi, Khem Raj | Devkota, Hari Prasad | Watanabe, Takashi | Yahara, Shōji

Eleven phenolic compounds, quercetin (1), quercetin 3- O -β- d -galactopyranoside (2), quercetin 3- O -(6″- O -galloyl)-β- d -galactopyranoside (3), quercetin 3- O -(6″- O -caffeoyl)-β- d -galactopyranoside (4), quercetin 3- O -β- d -glucopyranoside (5), rutin (6) quercetin 3- O -α- l -arabinopyranoside (7), quercetin 3- O -α- l -arabinofuranoside (8), protocatechulic acid (9), gallic acid (10) and chlorogenic acid (11), were isolated from the flowers of Aconogonon molle , a Nepalese medicinal plant. Structures of these compounds were elucidated on the basis of spectroscopic methods. All these compounds were isolated for the first time from flowers, and five compounds (4 , 5 , 8 , 9 and 11) were isolated for the first time from A. molle. All of these isolated compounds were evaluated for their in vitro antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl radical-scavenging method. Quercetin (1), quercetin glycosides (2 – 8) and gallic acid (10) exhibited potent antioxidant activity.

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