Alkaloids from stem bark and leaves of Peschiera buchtieni

Azoug, M.; Loukaci, A.; Richard, B.; Nuzillard, J.M.; Moreti, C.; Zeches-Hanrot, M.; Le Men-Olivier, L.

Alkaloids from stem bark and leaves of Peschiera buchtieni

1995

During an investigation of the stem bark and leaves of Peschiera buchtieni, 34 alkaloids were isolated. Eight new alkaloids were obtained from the stem bark, N-methyl-pericyclivine, 18,19(R)-dihydroxycoronaridine, chloromethylene affinisinium, demethylaccedinisine, 18-hydroxyaffinisine, buchtienine, 3-hydroxytetrahydroolivacine and demethylceridimine. The known alkaloids from the stem bark were coronaridine, voaphylline, coronaridine hydroxyindolenine, heyneanine, eglandine, eglandulosine, 19-epi-heyneanine, voachalotine, ochropamine, olivacine, ibogamine, affinisine, N-oxyaffinisine, vallesamine, (E)-isositsirikine, voaphylline hydroxyindolenine, normacusine B, janetine, 3,14-dihydroolivacine, 3'(R/S)-hydroxy-N-demethyl-tabernamine, 4',17 beta-dihydrotchibangensine, ceridimine and N-demethyltabernamine. Apodine, voacristine, voacristine hydroxyindolenine and olivacine were identified in leaves.

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