Nutrition, longevity, and aging
1979
Data from animal studies have demonstrated the interrelationships between and among nutrition, longevity and aging. Unrestricted feeding of animals throughout life (resulting in rapid growth and accumulation of excess body fat) decreases age at death. On the other hand, restriction of total food intake begun early during postweaning life (resulting in decreased growth and adult body size), increases mean age at death and alters the pattern of diseases associated with old age. Diet-related diseases associated with old age include diabetes, obesity, cancer, cardiovascular disease, and osteoporosis. The composition of the diet affects longevity depending on the age of the organism when the dietary change is started, the total level of food intake, and the mode of feeding. The significance of these findings must be evaluated in humans.
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