Application of the AhR reporter gene assay for the determination of PCDD/Fs and DL-PCBs in feed samples

Piskorska-Pliszczyńska Jadwiga; Małagocki Paweł; Furga Beata; Gembal Magdalena; Cebulska Joanna

Application of the AhR reporter gene assay for the determination of PCDD/Fs and DL-PCBs in feed samples

2017

Piskorska-Pliszczyńska Jadwiga | Małagocki Paweł | Furga Beata | Gembal Magdalena | Cebulska Joanna

Introduction: Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) belong to a well-known group of pollutants. Present in feedstuffs, they bioaccumulate in tissues of food-producing animals. Food is the source of over 90% of human PCDD/Fs and DL-PCBs intake. Thus, feed control is one of the pillars of the EU strategy and a mean of reducing human exposure. The article presents AhR based reporter gene bioassay method for PCDD/Fs and DL-PCBs analysis in feed and its validation results.

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