Association between infection with Toxoplasma gondii and psychiatric disorders

Maisarah, Alia; Mohamad, Suharni; Husain, Maruzairi et al.

Association between infection with Toxoplasma gondii and psychiatric disorders

2022

Maisarah, Alia | Mohamad, Suharni | Husain, Maruzairi et al.

Toxoplasmosis is one of the world's most prevalent zoonoses. The causative agent, Toxoplasma gondii (Nicolle et Manceaux, 1908) is a facultative heteroxenic, polyxenic apicomplexan protist. There are several potential pathways of transmission within and between host species. Most infections with T. gondii result from close contact with pets/cats, ingestion of tissue cysts in undercooked meat of infected animals, and oocysts from food or water contaminated by feline faeces. Recently, epidemiological studies have shown that T. gondii infection plays a prominent role in the pathogenesis of several psychiatric disorders. This report reviews the association between T. gondii infection and patients with psychiatric disorders, particularly schizophrenia, depressive disorders and bipolar disorders.

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