Study The Effect of Ketoconazole and Vitamin E on Some Arabi Ram Sperm Characteristics

Khairi G. Alrikabi

Study The Effect of Ketoconazole and Vitamin E on Some Arabi Ram Sperm Characteristics

1970

Khairi G. Alrikabi

      Experiment  aims to investigate the effect of ketoconazole on certain sperm characteristic of Arabi rams .fifteen adult rams were randomly assigned in 3 groups, 5 animals in each group which treated daily as the following : control group, ket group received orally (25 mg/kg body weight of ketoconazole and ket-E group received (25 mg/kg body weight of ketoconazole+50 mg vit E / head). The study lasted 28 days.  Collection of semen was done each week by artificial vagina. Sperm traits were estimated in addition to assessment the level of testosterone and some anti_oxidative enzyme and oxidative marker (MDA ). It was concluded that orally administered Ketoconazole has a negative impact on fertility of Arabi rams and vit E at 50 mg/head can prevent adverse effect of ketoconazole on sperm characteristic of Arabi rams.

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