Culturing circular ssDNA viruses for the production of vaccines Inventors

Meerts, Peter; Nauwynck, Hans; Misinzo, Gerald

Culturing circular ssDNA viruses for the production of vaccines Inventors

2007

Meerts, Peter | Nauwynck, Hans | Misinzo, Gerald

The present invention relates to the use of interferon in the in vitro cultivation of animal circular ssDNA virus such as Porcine Circovirus 2 or human TT virus in an animal cell line. Increased titres of animal circular ssDNA virus are obtained by addition of interferons or agents which ensure the production of endogenous interferons by said cell line.

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