General characteristic of parasitologic situation at the exclusion zone, some aspects of new conditions influence on separate systematic groups of mammal parasites Polesye State Radiation and Nature Reserve of the Republic of Belarus were presented. Research of helminth fauna and helminthological situation was realized by an example of 1 European bison, 7 mooses, 20 roe deers, 26 boars, 25 wolves, 50 racoon dogs, 6 foxes and 3 beavers. Scatoscopy of the animal excrements was realized by Kalantaryan method with saturated solution of sodium saltpeter, Berman method. Research results revealed 66 helminth species belonging to 4 classes and 34 families. There were found 10 parasite species at bison, 16 – at mosses, 17 – at roe deers, 16 – at boars, 8 – at deers, 23 – at wolves, 13 – at raccoon dogs, 13 – at foxes, 9 – at badgers and 1 – at beavers. Analyze of helminthofauna of the analyzed area showed that the nature reserve had its own helminthes complex. A lot of stated helminth species were parasites with a wide range of hosts, including domestic animals, and cattle. Wolves, foxes and raccoon dogs were hosts of some custodies invasions. Carnivorous animals and murine rodents were hosts of trichinosis invasion, which was stated at 41,2 % of raccoon dogs, 33,3 % of foxes and 16,7 % of wolves. Also trichinas were stated at bank vole (1,3%), yellow-necked mouse (2,7%), and house mouse (16,6%)

The information on necessity of carrying out of monitoring and purposeful scientific research on studying of infectious diseases of wild animals in hunting farms of the Republic of Belarus was presented in order to lower their negative influence on state of a population of resource species of wild animals. On the territory of Belarus in the studied wild animals there were stated 42 infectious diseases, including 36 ones which were the reasons of death of valuable hunting and fur-bearing animals. The greatest threat from infectious diseases was represented by rinderpest, pasteurilosis, salmonellosis, furiousness, necrobacillosis, listeriosis, botulism, tuberculosis, pseudorabies, the Siberian ulcer and hoof-and-mouth disease. Many diseases represent danger to human beings, the other lead to a various degree losses for the hunting economy of the country

There was presented a territorial analysis of epizootic situation on rabies in the administrative districts and regions of the Republic of Belarus in the period from 1986 up to 2008. The situation of strain was stated on the territory of Vitebsk (28, 4%) and Minsk (20,2%) regions. The most stable epizootic situation was stated in Shumilin, Braslavsk and Vitebsk districts of Vitebsk region, as well as in Vologin and Minsk districts of Minsk region. Only in 1990 and 1997 there were stated no cases of rabies in Brest and in 1996 in Mogilev regions. In other years no regions were free from this infection. Economic damage from rabies cases in agricultural animals in period 1986-2008 was over 2 milliard of Belarusian rubles.