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Identification and molecular characterization of a rabbit hemorrhagic disease virus variant (KV0801) isolated in Korea
2009
Yang, D.K., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Kim, B.H., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Lee, K.W., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Kim, J.Y., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Kim, H.J., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Choi, S.S., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Chun, J.E., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Son, S.W., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea
Rabbit hemorrhagic disease (RHD) is caused by RHD virus (RHDV) and is one of the most fatal diseases of rabbits. Acute death of rabbits occurred in a farm located in the Gyeonggi province of South Korea. The virus was isolated and confirmed as RHDV based on reverse transcription polymerase chain reaction and hemagglutination assay (HA), and the isolate was designated as KV0801. The nucleotide sequence was deduced. Molecular analysis showed that the KV0801 isolate can be classified as a pandemic antigenic variant strain, RHDVa. The VP60 nucleotide sequence and deduced amino acid homology between KV0801 and other Korean isolate, RHF89, which was isolated in 1988, were 92.1 and 94.3%, respectively. The pathogenicity of the KV0801 isolate at an HA titer ranging from 16,384 to 0.16 HA units was evaluated in five-month-old SFP rabbits. The rabbits inoculated with KV0801 isolate containing more than 1.63 HA units died within six days of inoculation. These results suggest that a highly pathogenic RHDVa is circulating in the rabbit populations of Korea.
Показать больше [+] Меньше [-]Detection of antibodies against infectious Borna disease virus - A comparison of three serological methods-
1992
Lee, D.S. (Cheju Nat'l Univ., Cheju (Korea Republic). Dept. of Veterinary Medicine)
A pathological observation on the experimental rabbit viral hepatitis
1992
Jyeong, J.S. (Kyungpook Animal Health Experimental Inst., Taegu (Korea Republic). ) | Kwon, Y.R. | Lee, C.S. (Kyungpook Nat'l Univ., Taegu (Korea Republic). Coll. of Veterinary Medicine) | Shin, T.K. (Cheju Nat'l Univ., Cheju (Korea Republic). Dept. of Veterinary Medicine)
Purinergic innervation on the isolated renal artery of rabbit
1991
Kim, J.H. (Gyeongsang National Univ., Chinju (Korea Republic). Coll. of Veterinary Medicine) | Kim, Y.K. (Pusan National Univ., Pusan (Korea Republic). Coll. of Medicine)
Further characterization of the causative virus of rabbit viral hepatitis, so-called rabbit haemorrhagic disease in Korea
1992
Jyeong, J.S. (Kyungpook Animal Health Experimental Institute, Taegu (Korea Republic)) | Jeong, K.S. | Lee, C.S. (Kyungpook National University, Taegu (Korea Republic). College of Veterinary Medicine) | Shin, T.K. (Cheju National University, Cheju (Korea Republic). Department of Veterinary Medicine)
Evaluation of a cell enzyme-linked immunosorbent assay for the detection of borna disease virus antibodies in experimentally infected animals
1992
Lee, D.S. (Cheju National University, Cheju (Korea Republic). Department of Veterinary Medicine)
Effects of gender on the pharmacokinetics and metabolite formation of sulfamethazine in the rabbit
1992
Yun, H.I. (Chungnam Nat'l Univ., Taejon (Korea Republic). Coll. of Veterinary Medicine) | Park, I.H. (Chungnam Nat'l Univ., Taejon (Korea Republic). Coll. of Natural Science)
