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Cardiovascular changes after bone marrow transplantation in dogs with mucopolysaccharidosis I
1990
Gompf, R.E. | Shull, R.M. | Breider, M.A. | Scott, J.A. | Constantopoulos, G.C.
Five dogs with mucopolysaccharidosis I, 3 of which had been treated with bone marrow transplantation (BMT), were evaluated for 20 months with electrocardiography, thoracic radiography, and M-mode and 2-dimensional echocardiography. Treated and untreated (control) dogs had widened P waves on ECG. Thoracic radiographs remained normal for all dogs throughout the study. Thickening of the mitral valve was observed on echocardiograms of dogs in both groups, but the untreated dogs appeared to have thicker valves. Concentrations of glycosaminoglycans in the mitral valves and myocardium were higher in control dogs than in treated dogs. Markedly large aortic root diameters were observed on echocardiograms in both untreated dogs, but aortic root diameters remained normal in treated dogs. Echocardiography, but notelectrocardiography, was useful in monitoring heart enlargement in each dog. Dogs treated with BMT generally had less-severe cardiac changes and slower disease progression than control dogs.
Показать больше [+] Меньше [-]Hemodynamic effects of carbon dioxide during intermittent positive-pressure ventilation in horses
1990
The hemodynamic effects of high arterial carbon dioxide pressure (PaCO2) during anesthesia in horses were studied. Eight horses were anesthetized with xylazine, guaifenesin, and thiamylal, and were maintained with halothane in oxygen (end-tidal halothane concentration = 1.15%). Baseline data were collected while the horses were breathing spontaneously; then the horses were subjected to intermittent positive-pressure ventilation, and data were collected during normocapnia (PaCO2, 35 to 45 mm of Hg), moderate hypercapnia (PaCO2, 60 to 70 mm of Hg), and severe hypercapnia (PaCO2, 75 to 85 mm of Hg). Hypercapnia was induced by adding carbon dioxide to the inspired gas mixture. Moderate and severe hypercapnia were associated with significant (P < 0.05) increases in aortic blood pressure, left ventricular systolic pressure, cardiac output, stroke volume, maximal rate of increase and decrease in left ventricular pressure (positive and negative dP/dtmax, respectively), and median arterial blood flow, and decreased time constant for ventricular relaxation. These hemodynamic changes were accompanied by increased plasma epinephrine and norepinephrine concentrations. Administration of the beta-blocking drug, propranolol hydrochloride, markedly depressed the response to hypercapnia. This study confirmed that in horses, hypercapnia is associated with augmentation of cardiovascular function.
Показать больше [+] Меньше [-]Electrocardiogram studies in llamas
1989
Bastres, M.C. (Yokohama Univ. (Japan). Faculty of Engineering) | Sakabe, N. | Yasuda, J. | Too, K.
Studies on electrocardiogram of the normal Korean native cattle-(2)-Wave forms and amplitudes of the unipolar precordial chest leads
1993
Choi, I.H. | Kim, S.Y. | Kim, N.S. (Chonbuk National University, Chonju (Korea Republic). College of Veterinary Medicine) | Suh, D.S. (Chonnam National University, Kwangju (Korea Republic). College of Veterinary Medicine)
Electrocardiographic surrogates of structural myocardial alterations in the Dorper sheep heart
2005
Ker, J. (Pretoria Univ. (South Africa). Dept. of Physiology) | Webb, E.C.
Standardization of a new precordial chest lead system in the dog
1990
Nunes, A.A. | Moffa, P.J. | Iwasaki, M.