For the determination of efficiency of a new produced in the Republic of Belarus preparation Ehkvikar there was modeled a test with a diaphoresis of guinea pigs by means of their staying in a thermostat at a temperature of 45-50 deg C in course of 30 minutes. Before and after the test there was taken a blood test for its analysis. Results of the experiment showed that together with sudo the animals lost 1-2 % of their body. There was stated the increasing of all blood corpuscles as well as lowering in 1,3-1,47 times of such elements as chlorine, sodium, potassium, and also T lymphocytes and bursa-derived lymphocytes. Application Ehkvikar promoted the stabilization of biochemical and morphological parameters of blood, and also the immune status of laboratory animals. Thus, Ehkvikar preparation promoted the compensation of losses of electrolytes with sudor of guinea pigs and in future can be studied by an example of horses for completion of electrolytes losses in the conditions of increased physical exercises.

Study of peculiar features of protein metabolism of healthy colts in the first three months of life was realized in the conditions of the Republic of Belarus. Research results showed that there was a tendency of increasing of hemoglobin concentration up to 150,270+/- 4,73 g/l, number of total protein of blood serum – up to 60,33 +/- 1,33 g/l, and the decreasing of uric acid up to 97,33 +/- 10,72 micromole /l. Quantity of beta-1 and alpha globulin fractions of serum protein fluctuated a little – from 10,78 +/- 3,69% up to 8,44 +/- 1,24% and from 25,12 +/- 4,84% up to 22,06 +/- 4,93%, respectively. The most essential changes of protein metabolism were stated at two month old colts, which had urea concentration of 5,25 +/- 0,23 micromole/l, alanine aminotransferase activity – 66,92 +/- 3,16 units/l, creatine content increased up to 77,37 +/- 5,83 micromole /l; and there was the lowering of aspartate transaminase level up t159,5 +/- 8,1units/l. There was stated the lowering of albumin quantity up to 32,07 +/- 2,19%, and increasing of alpha-1, alpha2- and beta2- globulin fractions up to 7,52 +/- 1,23%, 14,98 +/- 1,41%, 11,82 +/- 1,04%, respectively. At the age of three months the quantity of urea and creatinine in blood serum of colts remained at the same level, alanine aminotransferase activity decreased on 21,56%, and aspartate transaminase increased up to 204,33 +/- 10,37 units/l. At this period the quantity of albumin fractions was 44,56 +/- 6,59%., concentration of alpha-1, alpha2- and beta2- globulins decreased on 10,64%, 30,04% and 34,52%, respectively

Results of chemical and toxicological estimation of an energized preparation, intended for increasing of performance ability and sports qualities of horses realized in the conditions of the Republic of Belarus were presented. The energized preparation included honey, lactalbumin hydrolyzate, pollen hydrolyzate, and teotropin. Chemical and toxicological estimation of the preparation included determination of physical, chemical and pharmacological compatibility of components of the preparation, acute and chronic toxicological characteristics, skin-resorbtive poison after single and long-term application at horse skin, topical-product-induced irritation and allergic action of the preparation. Research results showed that all components of the preparation were compatible among themselves. The preparation proved to be a low-hazardous substance (substance hazard category 4) and did not possess skin-absorptive, local-irritating and allergic action.

In the conditions of the Republic of Belarus there was realized a study of age-specific features of level of erythrocytes, haemoglobin in blood, activity of aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alkaline phosphatase, as well as concentration of calcium, phosphorous, magnesium and ferrum in blood serum of suckling colts in the first 6 months of life. In the studied animals there was stated increased levels, haemoglobin and ferrum concentration in blood, but during the 6th month of life the same indexes decreased considerably. The most considerable changes оf blood serum enzymatic activities occurred at the age of 2 and 6 months. Thus, during the 2nd month of life a raise in ALAT, LDH activity, calcium and phosphorus concentration was noticed. At the age of 6 months ALAT and ASAT levels increased, and LDH activity, magnesium and phosphorus concentration decreased. During the first 6 months of life the ALP activity was on a high level and underwent no reliable changes. As the research showed, blood serum enzymatic activity and concentration of calcium, phosphorus, magnesium and ferrum depended on colt age and change at the process of growth and development of animals.