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Models to assess the risk of introduction of selected animal viral diseases through the importation of live animals as a key part of risk analysis Полный текст
2021
Gierak Anna | Śmietanka Krzysztof
Models to assess the risk of introduction of selected animal viral diseases through the importation of live animals as a key part of risk analysis Полный текст
2021
Gierak Anna | Śmietanka Krzysztof
Introduction of an animal viral disease, especially a notifiable disease, into an importing country or region free from the disease may lead to serious epidemiological consequences and economic losses. Trade in live animals is historically considered one of the most important risk pathways. To estimate the magnitude of such risk, the likelihood of a virus’ entry into a country and the consequences of this event should be jointly evaluated. Depending on data availability, the urgency of the problem and the detail level of the objectives, a risk assessment may be conducted in a qualitative, semi-quantitative or quantitative way. The purpose of this review was firstly to provide a brief description of each step of the risk analysis process, with particular emphasis on the risk assessment component, and subsequently to supply examples of different approaches to the assessment of the risk of the introduction of selected animal viral diseases. Based on the reviewed models, the overall likelihood of introduction of particular diseases was generally estimated as low. The output risk value was strongly dependent on the duration of the silent phase of the epidemic in the country of origin. Other parameters with some bearing upon the risk derived from the epidemiological situation in the country of origin and the biosecurity or mitigation measures implemented in the country of destination. The investigated models are universal tools for conducting assessment of the risk of introduction of various animal diseases to any country. Their application may lead to timely implementation of appropriate measures for the prevention of the spread of a disease to another country or region.
Показать больше [+] Меньше [-]Models to assess the risk of introduction of selected animal viral diseases through the importation of live animals as a key part of risk analysis Полный текст
2021
Gierak, Anna | Śmietanka, Krzysztof
Introduction of an animal viral disease, especially a notifiable disease, into an importing country or region free from the disease may lead to serious epidemiological consequences and economic losses. Trade in live animals is historically considered one of the most important risk pathways. To estimate the magnitude of such risk, the likelihood of a virus’ entry into a country and the consequences of this event should be jointly evaluated. Depending on data availability, the urgency of the problem and the detail level of the objectives, a risk assessment may be conducted in a qualitative, semi-quantitative or quantitative way. The purpose of this review was firstly to provide a brief description of each step of the risk analysis process, with particular emphasis on the risk assessment component, and subsequently to supply examples of different approaches to the assessment of the risk of the introduction of selected animal viral diseases. Based on the reviewed models, the overall likelihood of introduction of particular diseases was generally estimated as low. The output risk value was strongly dependent on the duration of the silent phase of the epidemic in the country of origin. Other parameters with some bearing upon the risk derived from the epidemiological situation in the country of origin and the biosecurity or mitigation measures implemented in the country of destination. The investigated models are universal tools for conducting assessment of the risk of introduction of various animal diseases to any country. Their application may lead to timely implementation of appropriate measures for the prevention of the spread of a disease to another country or region.
Показать больше [+] Меньше [-]Clinical chemistry investigations in recumbent and healthy German Holstein cows after the fifth day in milk Полный текст
2019
Weber, Jim | Zenker, Markus | Köller, Gábor | Fürll, Manfred | Freick, Markus
Clinical chemistry investigations in recumbent and healthy German Holstein cows after the fifth day in milk Полный текст
2019
Weber, Jim | Zenker, Markus | Köller, Gábor | Fürll, Manfred | Freick, Markus
Recumbency is a frequent symptom occurring throughout lactation. Its cause can be related to the energy or mineral metabolism, or to trauma or infectious diseases. We compared various clinical chemistry parameters between healthy and recumbent cows and between cows with different causes of recumbency and determined if hypocalcaemia manifests in later lactation. Recumbent (n = 32) and healthy (n = 32) German Holstein cows were studied. After clinical examination, a serum sample was taken to measure the concentrations of Mg, Ca, Fe, Na, K, Pi, β-hydroxybutyrate, total bilirubin, non-esterified fatty acids (NEFA), urea, and creatinine as well as activities of alkaline phosphatase, aspartate aminotransferase (AST), creatine kinase (CK), and γ-glutamyl transferase in recumbent cows > 5 d in milk and control cows matched for age, lactation number, and pregnancy stage. In recumbent cows, mean serum concentrations of NEFA, bilirubin, and CK were statistically higher, while those of Fe, K, and Pi were significantly lower. Parameters compared between different recumbency diagnoses showed some descriptive Fe, K, urea, and AST differences, but these were not statistically significant. The results show that only a limited number of parameters have diagnostic besides therapeutic value. Although of minor importance in our study, hypocalcaemia should be considered a cause of recumbency, even outside the typical risk period of parturient paresis.
Показать больше [+] Меньше [-]Clinical chemistry investigations in recumbent and healthy German Holstein cows after the fifth day in milk Полный текст
2019
Weber Jim | Zenker Markus | Köller Gábor | Fürll Manfred | Freick Markus
Recumbency is a frequent symptom occurring throughout lactation. Its cause can be related to the energy or mineral metabolism, or to trauma or infectious diseases. We compared various clinical chemistry parameters between healthy and recumbent cows and between cows with different causes of recumbency and determined if hypocalcaemia manifests in later lactation.
Показать больше [+] Меньше [-]Prevalence of infectious diseases on dairy farms classified on the basis of their biosecurity score Полный текст
2022
Perillo Laura | Cascone Giuseppe | Antoci Francesco | Piccione Giuseppe | Giannetto Claudia | Salonia Rosario | Salina Felice | Giudice Elisabetta | Monteverde Vincenzo | Licitra Francesca
The aim of the study was to investigate the relationship between biosecurity as scored on the Italian National Animal Welfare Reference Centre (Centro di Referenza Nazionale per il Benessere Animale – CReNBA) checklist and the prevalence of Mycobacterium avium subsp. paratuberculosis, Chlamydophila abortus and Neospora caninum on dairy farms located in Ragusa, Italy.
Показать больше [+] Меньше [-]Treatment of selected canine dermatological conditions in Portugal – a research survey Полный текст
2018
Oliveira, Ana | Devesa, Joana S.P. | Hill, Peter B. | Silva, Vanessa | Poeta, Patrícia
Treatment of selected canine dermatological conditions in Portugal – a research survey Полный текст
2018
Oliveira, Ana | Devesa, Joana S.P. | Hill, Peter B. | Silva, Vanessa | Poeta, Patrícia
Introduction: Staphylococcus pseudintermedius and Malassezia pachydermatis often cause skin diseases in dogs. Material and Methods: An online survey was e-mailed to veterinary practices nationwide covering demographics, diagnosis methods, and oral and topical treatment options. Of the 740 surveys sent, 100 complete replies were obtained. Results: The majority of clinicians were unaware of the existence of the International Society for Companion Animal Infectious Diseases guidelines or did not follow them (53%). Oral antibiotics were used universally for superficial bacterial folliculitis treatment, particularly amoxicillin-clavulanic acid (100%), cephalexin (94%), enrofloxacin (67%), or marbofloxacin (60%). For fold dermatitis (FD) and otitis externa (OE), oral antibiotics were also given as treatment in 88% and 82% of cases, respectively. Oral antifungals were often prescribed for generalised Malassezia dermatitis (85%), FD (70%), and OE (59%). S. pseudintermedius and M. pachydermatis were frequently treated topically, particularly with antibacterials or antifungals only, or a combination of antibacterials, antifungals, and glucocorticoids. Alternative options such as honey-based products were not frequently used. Conclusion: Our survey suggests that oral antibiotics are overused by Portuguese clinicians despite the spread of antibiotic resistant S. pseudintermedius. Oral antibiotics and antifungals are commonly prescribed for skin conditions manageable with topical treatments.
Показать больше [+] Меньше [-]Treatment of selected canine dermatological conditions in Portugal – a research survey Полный текст
2018
Oliveira Ana | Devesa Joana S.P. | Hill Peter B. | Silva Vanessa | Poeta Patrícia
Introduction:Staphylococcus pseudintermedius and Malassezia pachydermatis often cause skin diseases in dogs.
Показать больше [+] Меньше [-]Molecular microbiological characteristics of gingival pockets in the periodontal diseases of dogs Полный текст
2023
Polkowska Izabela | Tymczyna-Borowicz Barbara | Gołyńska Magdalena | Nowicka Beata
Canine periodontitis results among other factors from a disturbed balance of dental plaque microflora and an inadequate host inflammatory response to a stimulus. This investigation sought to identify microorganisms associated with canine periodontitis.
Показать больше [+] Меньше [-]Whole genome sequence of Brucella melitensisl local isolate from an infected goat in Malaysia Полный текст
2016
Mohd Mokhtar Arshad | Ramlan Mohamed | Shuhaila Mat Sharani | Hardy Abu Daud | Omer Khazaal Sallou | Mohd Azam Khan Goriman Khan | Hirzahida Mohd. Padil
Brucellosis in goats is mainly caused by the bacterium Brucellamelitensis, which is one of the most important pathogenic species in the world. In Malaysia, the annual prevalence data of brucellosis was recorded in goats and the control strategy of the disease basedon test and cull of infected animals. This strategy has caused huge economic losses to farmers and government alike. Therefore, whole genome sequencing of B. melitensis local strain is essential forimproving the current vaccine. B. melitensis strain VRI 6530/11 wasobtained from veterinary research institute biobank, Ipoh. The strain was submitted for classical identification procedures and the total genomic DNA was extracted by using DNeasy blood and tissue kit(QIAGEN). The concentration and purity of DNA were determined by using agarose gel electrophoresis and spectrophotometer (DNA/RNA) assay respectively. The genome was sequenced by using IlluminaHiSeq platform with insert size ~200 bp. A total of 1.0 Gb data was generated from the sample. More than 95% of sequencing data was retained in the sample after quality filtering, this indicatethe sequencing reads are of high quality. Final assembly had 33 scaffolds with total size ~3.28 Mb, 44 contigs, GC content is 57.25%, N50 is 293,291. A total of 3,238 protein coding genes, 48 tRNAs and 3rRNAs were predicted and over 87% of the genes were functionally annotated. Genome sequencing of a local B. melitensis strain is the first of its kind in Malaysia and work from this study can contribute towards the development of a new effective vaccine for the control ofthe disease in the country.
Показать больше [+] Меньше [-]Changes in leukocyte populations of cows with milk fever or displaced abomasum after calving Полный текст
2013
Ohtsuka, Hiromichi | Fukuda, Shigeo | Kudo, Katsunori | Tomioka, Michiko | Koiwa, Masateru | Kimura, Kayoko
Most of the metabolic diseases of dairy cows occur within the first 2 wk after calving, and cows with a metabolic disease are prone to infectious diseases. Although metabolic diseases are generally recognized as a risk factor for infectious diseases owing to the associated decrease in immune function, the difference in immune status between cows with milk fever (MF) or displaced abomasum (DA) during the lactation period has not been clarified. Therefore, the peripheral blood leukocyte populations in 38 multiparous Holstein cows from 1 herd were analyzed after calving. The cows were divided into 3 groups according to health: 21 cows that remained clinically healthy throughout the experimental period (control group), 9 cows that had MF on the day of calving, and 8 cows with an onset of DA within 4 wk after calving. The T- and B-cell numbers were lowest at week 0, and they increased gradually after calving. There was no significant difference between the 3 groups in the number of each subset of leukocytes on the day of calving, but the number of CD8+ T-cells was significantly lower in the MF and DA groups than in the control group at week 1. The numbers of CD4+, CD8+, and WC1+ T-cells tended to be lower in the DA group than in control group from weeks 4 to 12, a tendency not observed in the MF group. These data suggest that when cows have DA around the time of calving, their lymphocyte numbers remain lower until 12 wk after calving.
Показать больше [+] Меньше [-]Resource mapping and emergency preparedness to infectious diseases in human and animal populations in Kibaha and Ngorongoro districts, Tanzania Полный текст
2012
E.D. Karimuribo | B. Jones | M.I. Matee | D.M. Kambarage | S. Mounier-Jack | M.M. Rweyemamu
A rapid situation analysis was conducted in Kibaha and Ngorongoro districts in Tanzania to map resources as well as analysing emergency preparedness to infectious diseases in animal (domestic and wild) and human populations. Kibaha was chosen as a district close to a commercial city (Dar es Salaam) while Ngorongoro represented a remote, border district with high interactions between humans, domestic and wild animals. In this study, data on resources and personnel as well as emergency preparedness were collected from all wards (n = 22), human health facilities (n = 40) and livestock facilities in the two districts using interview checklists and questionnaires. Descriptive statistics for resources were calculated and mapped by district. Kibaha district had a higher human population density, more health workers, better equipped health facilities and better communication and transport systems. On the other hand, Ngorongoro had a higher population of livestock and more animal health facilities but a poorer ratio of animal health workers to livestock. The average ratio of health personnel to population in catchment areas of the health facilities was 1:147 (range of 1:17−1:1200). The ratio of personnel to human population was significantly higher in Kibaha (1:95) than in Ngorongoro (1:203) district (p = 0 < 0.001). Considering the limited resources available to both human and animal health sectors and their different strengths and weaknesses there are opportunities for greater collaboration and resource-sharing between human and animal health for improved surveillance and emergency-preparedness.
Показать больше [+] Меньше [-]A socio-economic approach to One Health policy research in southern Africa Полный текст
2012
Kim A. Kayunze | Angwara D. Kiwara | Eligius Lyamuya | Dominic M. Kambarage | Jonathan Rushton | Richard Coker | Richard Kock | Mark M. Rweyemamu
A socio-economic approach to One Health policy research in southern Africa Полный текст
2012
Kim A. Kayunze | Angwara D. Kiwara | Eligius Lyamuya | Dominic M. Kambarage | Jonathan Rushton | Richard Coker | Richard Kock | Mark M. Rweyemamu
One-health approaches have started being applied to health systems in some countries in controlling infectious diseases in order to reduce the burden of disease in humans, livestock and wild animals collaboratively. However, one wonders whether the problem of lingering and emerging zoonoses is more affected by health policies, low application of one-health approaches, or other factors. As part of efforts to answer this question, the Southern African Centre for Infectious Disease Surveillance (SACIDS) smart partnership of human health, animal health and socio-economic experts published, in April 2011, a conceptual framework to support One Health research for policy on emerging zoonoses. The main objective of this paper was to identify which factors really affect the burden of disease and how the burden could affect socio-economic well-being. Amongst other issues, the review of literature shows that the occurrence of infectious diseases in humans and animals is driven by many factors, the most important ones being the causative agents (viruses, bacteria, parasites, etc.) and the mediator conditions (social, cultural, economic or climatic) which facilitate the infection to occur and hold. Literature also shows that in many countries there is little collaboration between medical and veterinary services despite the shared underlying science and the increasing infectious disease threat. In view of these findings, a research to inform health policy must walk on two legs: a natural sciences leg and a social sciences one.
Показать больше [+] Меньше [-]A socio-economic approach to One Health policy research in southern Africa Полный текст
2012
Kayunze, Kim A.(Sokoine University of Agriculture Development Studies Institute) | Kiwara, Angwara D.(Muhimbili University of Health and Allied Sciences Institute of Development Studies) | Lyamuya, Eligius(Muhimbili University of Health and Allied Sciences) | Kambarage, Dominic M.(Sokoine University of Agriculture) | Rushton, Jonathan(Royal Veterinary College) | Coker, Richard(Mahidol University) | Kock, Richard(Royal Veterinary College) | Rweyemamu, Mark M.(Sokoine University of Agriculture)
One-health approaches have started being applied to health systems in some countries in controlling infectious diseases in order to reduce the burden of disease in humans, livestock and wild animals collaboratively. However, one wonders whether the problem of lingering and emerging zoonoses is more affected by health policies, low application of one-health approaches, or other factors. As part of efforts to answer this question, the Southern African Centre for Infectious Disease Surveillance (SACIDS) smart partnership of human health, animal health and socio-economic experts published, in April 2011, a conceptual framework to support One Health research for policy on emerging zoonoses. The main objective of this paper was to identify which factors really affect the burden of disease and how the burden could affect socio-economic well-being. Amongst other issues, the review of literature shows that the occurrence of infectious diseases in humans and animals is driven by many factors, the most important ones being the causative agents (viruses, bacteria, parasites, etc.) and the mediator conditions (social, cultural, economic or climatic) which facilitate the infection to occur and hold. Literature also shows that in many countries there is little collaboration between medical and veterinary services despite the shared underlying science and the increasing infectious disease threat. In view of these findings, a research to inform health policy must walk on two legs: a natural sciences leg and a social sciences one.
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