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Результаты 11-20 из 33
Influence of thyroid function on the pharmacokinetics of gentamicin in pigs.
1986
Riond J.L. | Dix L.P. | Riviere J.E.
Cardiovascular and pharmacokinetic effects of isoxsuprine in the horse.
1986
Matthews N.S. | Gleed R.D. | Short C.E. | Burrows K.
Theophylline and dyphylline pharmacokinetics in the horse.
1985
Ayres J.W. | Pearson E.G. | Riebold T.W. | Chang S.F.
Pharmacokinetics, effects on renal function, and potentiation of atracurium-induced neuromuscular blockade after administration of a high dose of gentamicin in isoflurane-anesthetized dogs.
1996
Martinez E.A. | Mealey K.L. | Wooldridge A.A. | Mercer D.E. | Cooper J. | Slater M.R. | Hartsfield S.M.
Pharmacokinetic model for cefazolin distribution during total hip arthroplasty in dogs.
1996
Marcellin Little D.J. | Papich M.G. | Richardson D.C. | DeYoung D.J.
Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses.
1989
Weckman T.J. | Tai C.L. | Woods W.E. | Tai H.H. | Blake J.W. | Tobin T.
Pharmacologic effects of alpha-methylfentanyl and 3-methylfentanyl, analogs of fentanyl, were investigated in mares. The ability of an 125I-labeled fentanyl radioimmunoassay (125I-RIA) to detect these methylated fentanyl analogs in individual and pooled urine samples from horses was evaluated. Also, the ability of 7 fentanyl antibodies to react with fentanyl and fentanyl derivatives (sufentanil, alfentanil, and carfentanil) was investigated. Mares were studied in a locomotor test to determine the amount of stimulation methylated fentanyl analogs might induce. Two mares each were given alpha-methylfentanyl at 1, 2, 4, 8, or 13 microgram/kg of body weight, IV, or 3-methylfentanyl at 0.4, 0.7, or 1 microgram/kg IV. The cross-reactivity of sufentanil, alfentanil, carfentanil, alpha-methylfentanyl, and 3-methylfentanyl with 7 fentanyl antibodies was studied, using the 125I-RIA. All fentanyl analogs, with the exception of alfentanil, cross-reacted well with a C1 antibody raised to fentanyl. Less satisfactory cross-reactivity was determined with 6 other antibodies raised to fentanyl derivatives. When the C1 antibody was combined with an iodinated analog to fentanyl, good detectability of alpha-methylfentanyl and 3-methylfentanyl, in terms of fentanyl equivalents, was obtained from urine samples of dosed mares. The ability of the 125I-RIA to detect methylated fentanyl analogs in forensic urine samples pooled in groups of up to 20 samples was evaluated. When these methylated analogs were administered to mares in doses that induced measurable locomotor stimulation, the analog's presence was readily detected in individual or pooled samples.
Показать больше [+] Меньше [-]Effect of probenecid administration on cephapirin pharmacokinetics and concentrations in mares.
1989
Juzwiak J.S. | Brown M.P. | Gronwall R. | Houston A.E.
Pharmacokinetics and bioavailability of ceftriaxone administered intravenously and intramuscularly to calves.
1988
Soback S. | Ziv G.
Pharmacokinetics of amikacin in pony foals after a single intramuscular injection.
1986
Brown M.P. | Gronwall R.R. | Martinez D.S. | Beal C.
Thiacetarsamide in dogs: disposition kinetics and correlations with selected indocyanine green kinetic values.
1986
Holmes R.A. | Wilson R.C. | McCall J.W.
