Analysis of the optimal scheme of doses and rates of combined administration of probiotic Dialakt and immunostimulant Alveozan was realized in the conditions of the Republic of Belarus by the example of 1500 broiler chickens of cross Kobb- 500. Chickens of the first (controlled) group were given only total ration, balanced with the main nutrients. For the chickens of the second group were administrated with immunostimulant Alveozan with water starting from one day old age, every day in dose of 10 mkg/kg of body weight once a day in course of 5 days successively and with 7 days interval till the end of growing period; and probiotic Dialakt was administrated with water in dose of 0,1-0,2 ml/head (10,0-20,0 mln microbial bodies) starting from one day old age, once a day in course of 5 days successively and with 6 and 14 days intervals till the end of growing period. Chickens of the third group were administrated Alveozan in dose of 10 mkg/kg of body weight with drinking water once a day in course of 5 days with 10 days interval till the end of growing period; and Dialakt in dose of 0,1-0,2 ml/head with drinking water starting from one day old age, every day in course of 5 days with 6 and 14 days interval till the end of growing period. The research results showed the following optimal regime of complex application of the analyzed preparations: immunostimulant Dialakt - in dose of 0,1-0,2 ml/head with drinking water starting from one day old age, once a day in course of 3 days successively with 6 and 14 days intervals till the end of growing period; and immunostimulant Alveozan - in doze of 10 mkg/kg of body weight with drinking water once a day in course of 5 days with 10 days interval till the end of growing period. Complex application of Dialakt and Alveozan promoted the increasing of organometric indexes, specific volume and size of thymus in 1,5-1,8 times (P less than 0,01), Fabritsiya bursa - in 2 times (P less than 0,01) and lien - on 11,1% (P less than 0,05)

Studying of efficiency of application of a natural biological control agent BioLAD obtained as a result of cultivation of Fusarium sambucinum fungus in feeding of broiler chickens was realized in the conditions of the Republic of Belarus. There were studied 100 broiler chickens of Ross-308 cross. Broiler chickens of the first (control) group were fed with standard diet with PK-5-1. Broiler chickens of the experimental groups starting from one day old age till the end of the growing period (41 days old) were fed with feed supplement BioLAD in different doses: 0,25 ml/head (second group), 0,5 ml/head (third group), 1 ml/head (fourth group). Research results showed that natural biological control agent BioLAD in dose of 0,5 ml/head made it possible to increase chicken live weight on 11,2 %, viability - on 4,2%. Feeding charges per 1 kg of live weight gain were1,89 kg (second group), 1,81 kg (third group), 1,90 kg (fourth group). It made it possible to decrease the combined feed charges on 6,4% (second group), on 10,4% (third group), and on 5,9% (fourth group). Application of biological control agent BioLAD had an effect on poultry growth activity, promoted high level of chickens viability, increased the indices of general and local protection, stimulated metabolic processes

In course of realized in the conditions of the Republic of Belarus evaluation of growing intensity and level of meat productivity depending on cattle sex there was conducted the scientific and economic experiment by an example of two groups of white-and-black bull-calves and heifer calves. In the first growing period the animals of experimental groups were fed with milk substitute. At the stage of completion of growing and fattening the bulls and heifers of experimental groups obtained ration containing haylage, plus 2 kg of flattened grains and 2 kg mixed fodders. Results of linear and weight indexes analysis showed that in changes of exterior of bulls and heifers of black-and-white breed there was noted a certain regularities in their growth and development. The most intensive growth and development of analyzed young cattle was stated at age from 6 till 12 months. At the same time, bulls exceeded heifers according to the main exterior indexes. According to the visual evaluation of bulls and heifers there were determined the differences in constitutional type

Growth and development of mixed bred Charollais x white-and-black young stock and black-and-white bull-calves since 8-month old age till and 15-month old age were studied in the conditions in the Republic of Belarus. In course of studied there were analyzed linear growth; young stock growth intensity; forage consumption; efficiency of experimental results. On the basis of obtained data there was determined the absolute growth rate of bull-calves at certain growing periods. Research results showed that dramatic changing of technology of management and feeding of mixed bred Charollais x white-and-black young stock bulls after weaning period caused the decrease of daily average live weight gain from 8-month old age till and 15-month old age in comparison with white-and-black cattle on 99 grams or 14%. Analysis of exterior of experimental animals confirmed the priority of mixed bred young cattle over white-and-black herdmates. They were characterized by massive corpus, wider and deeper barrel, wide withers, back and coupling

Research of the influence of biologically active preparations of natural origin on zoological indices and quality of animal products was studied by the example of their application in broiler chicken diets in the conditions of the Republic of Belarus. On the basis of realized research it was established, that application of biologically active substances immunoamplifier Alveozan, probiotic Dialakt, probiotic Bifidoflorin liquid, prebiotic Biofon and prebiotic Biofon AIL (produced in the Republic of Belarus) did not render negative effect on quality of animal products (all studied meat samples had high quality). The received results testify to necessity of complex application of the above-stated preparations. Application of biologically active preparations made it possible to increase livability of growing birds on 100%, average live weight increase from 1,9 up to 5,1%, daily average weight gain - from 1,9 up to 5,1%, improvement of feed conversion ratio - from 18,3 up to 21%. All studied biologically active preparations made it possible to restore the physiological environment in poultry intestines, normal flora, to suppress the growth of pathogenic microorganisms. The above mentioned preparations could be applied both with preventive, and with the medical purposes

The purpose of research is to study influence of fodder additive Water Trit liquid on dynamics of live weight, natural resistance and determination of an optimal dose for pigs on growing. Thanks to рН decrease of intestines contents and presence of organic acids the additive is applied for disease prevention. Presence of organic acids stimulates the development of useful Lactobacillus micro flora in intestines gleam. From the received data positive influence of the fodder additive on a gain of body weight is visible. In the beginning of experiment the difference in body weight of a control and a trial groups was insignificant and made from 9,2 kg to 9,4 kg in the experimental group, and 9,3 kg - in the control group. In the end of experiment the difference in body weight was essential: 28,6 kg, 30,5 kg, 29,5 kg in the trial groups and 28,05 kg in the control. After application of the fodder additive Water Trit liquid in the trial groups there were noted the raised daily average weight gains: on 2,6% in the second, on 13,4% (P less than 0,05) - in the third and on 8,5% - in the fourth group in relation to control group. For studying of the influence of the fodder additive on animal organism there was carried out the blood testing: phagocytosis, bactericidal activity of blood serum, lysozyme activity of blood serum. Indexes on phagocytal index at animal of the control and trial groups were in the beginning of experiment approximately at one level. At 45-day age the indexes in the second and fourth trial groups were above the control ones on 5,2% and 8,9%, respectively. By the end of the experiment the phagocytal index in all four groups changed insignificantly. At studying of lysozyme activity of blood serum at pigs the given research have shown, that at 30-day age the indexes in the third and fourth trial groups were above the control, and indexes in the first group were above the standard of the control. At 70-day age the highest lysozyme activity of blood serum was in the second trial group and has made +16,0% to the control. It is necessary to notice, that on the 70th day this indicator was above the control in all three trial groups

In the conditions of the Republic of Belarus there was analyzed the influence of inclusion into broiler chickens diets of probiotoc preparation Bifidoflorin zhidkij (liquid) and prediotic veterinary drug Biofon AIL on the natural resistance, hematopoiesis, growth, metabolic function, development and viability of broiler chickens. In course of the study there was analyzed the dynamics of total haemoglobin, total protein of blood serum, albumins and globulins of broiler chickens which were fed with veterinary drugs probiotoc Bifidoflorin zhidkij and prediotic Biofon AIL. Indexes of chicken viability and life weight gain were marked. Research results showed that application of the presented veterinary preparations rendered the growth promoting action, lowering of disease incidence, increasing of chicken viability, increasing of live weight gain and stimulation of metabolic processes in the most intense period of poultry growing. All these factors were expressed in highest degree after the combined application of the probiotic and prebiotic veterinary drugs.

Evaluation of safety and efficiency of application of immunostimulative drug Izambenum (C14H15IN2O) for stimulation of natural resistance (autarcesis) and immunologic responsiveness of chickens of laying breeds was realized in the conditions of the Republic of Belarus. Clinical and experimental investigation of Izambenum influence on poultry for the increasing of their resistance, activation of immunological response to vaccination against Newcastle disease, stimulation of their growth and development was realized. Research results showed that Izambenum influenced on level of morphological indexes of chicken blood: number of erythrocytes increased on 24%, hemoglobin - on 17%. Total protein in blood serum increased in all test period and number of lymphocytes increased and differential was 90-100%. Izambenum increased strains of post vaccination immunity to Newcastle disease. Bacterial growth-inhibitory activity decreased on the 27the day of life and increased at the same positions on the 34-41 days. Phagocyte activity of pseudoeosinophils increased in all test groups. Research results showed that Izambenum rendered growth and immunity stimulation action and increased their viability. Its immunostimulative action was conditioned by strengthening of cellular and to lower extent humoral immunity factors. Application of the preparation in period of Newcastle disease vaccination promoted the formation of long-lived immunity

Investigation of influence of probiotic Dialact and immunostimulant Alveozan on digesting of nutritive substances by broiler chickens of Kobb-500 cross, as well as control over their individual development were realized in the conditions of the Republic of Belarus. The first (control) group of chicken was given standard well-balanced ration. Chickens of the second group were administrated immunostimulant Alveozan in dose of 10 mkg/kg of live weight with drinking water once a day in course of 5 days, with 10 days interval till the end of the growing period. Chickens of the third group were administrated preparation Dialact in dose of 0,1-0,2 ml with drinking water once a day in course of 3 days, with 14 days interval till the end of growing period. Chickens of the fourth group were given Alveozan in dose of 10 microgram/kg of live weight once a day in course of 5 days with 10 days interval, and Dialact in dose 0,1-0,2 ml once a day in course of 3 days, with 6 and 14 days interval. Research results showed that complex application of probiotic Dialact and immunostimulant Alveozan increased the viability of chickens on 100%, average live weight - on 5,1%, average daily weight gain - on 5,1%. Administration of Dialact and Alveozan, both separately and in complex, increased the digestibility of nutritive substances of mixed fodders: application of nitrogen increased on 1,93-6,38%, application of calcium decreased on 10,41-12,54%, phosphorus use increased on 2,38%