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Antibody response to Raboral VR-G® oral rabies vaccine in captive and free-ranging black-backed jackals (Canis mesomelas)
2022
Koeppel,Katja N. | Geertsma,Peter | Kuhn,Brian F. | van Schalkwyk,Ockert L. | Thompson,Peter N.
Rabies is a zoonotic disease that remains endemic in large parts of southern Africa because of its persistence in wildlife and domestic dog vectors. The black-backed jackals (Canis mesomelas) is primarily the wildlife vector responsible for rabies outbreaks in northern parts of South Africa. Two trials were carried out to investigate antibody responses to the oral rabies vaccine Raboral V-RG® in black-backed jackals under captive and free-ranging conditions. In captive jackals 10/12 (83%; 95% confidence interval [CI]: 52% - 98%), seroconverted after single oral vaccination. Nine captive jackals had protective antibody titres (> 0.5 IU/mL) at 4 weeks (median: 2.1 IU/mL; inter quartile range [IQR]: 0.6-5.7) and 10 jackals had at 12 weeks (median: 3.5 IU/mL; IQR: 1.5-8.3) and three maintained antibody titres for up to 48 weeks (median: 3.4 IU/mL; IQR: 2.0-6.3). Four sites were baited with Raboral V-RG® vaccine for wild jackals, using fishmeal polymer and chicken heads. Baits were distributed by hand or from vehicle at three sites in north-eastern South Africa, with an average baiting density of 4.4 baits/km² and at one site in central South Africa, at 0.12 baits/km². This resulted in protective antibody titres in 3/11 jackals (27%; 95% Cl: 6-61) trapped between 3 and 12 months after baiting in north-eastern South Africa, compared with 4/7 jackals (57%; 95% Cl: 18-90) trapped after 3-18 months in central South Africa. This study shows the potential utility of oral rabies vaccination for the control of wildlife-associated rabies in north-eastern and central South Africa, but extensive studies with wider distribution of bait are needed to assess its potential impact on rabies control in wild jackals.
Показать больше [+] Меньше [-]Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material
2009
Markotter, W.(University of Pretoria Department of Microbiology and Plant Pathology) | York, D.(Molecular Diagnostic Services) | Sabeta, C.T.(Onderstepoort Veterinary Institute OIE Rabies Reference Laboratory) | Shumba, W.(Onderstepoort Veterinary Institute OIE Rabies Reference Laboratory) | Zulu, G.(Onderstepoort Veterinary Institute OIE Rabies Reference Laboratory) | Le Roux, K.(Allerton Veterinary Laboratory) | Nel, L.H.(University of Pretoria Department of Microbiology and Plant Pathology)
A rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously established phylogenetic groups from each genotype were included. The specificity of the rapid immunodiagnostic test compared favourably with the FAT and was found to detect all representatives of genotypes 1, 2, 3 and 4 in brain samples of either field cases or suckling mouse brain inoculates.
Показать больше [+] Меньше [-]A review of the infectious diseases of African wild ruminants
2001
Worthington, R.W. | Bigalke, R.D.
Aspects of rabies epidemiology in Tsumkwe District, Namibia
1997
Laurenson, K. (Stirling Univ. (United Kingdom). Dept. of Biological and Molecular Sciences) | Esterhuysen, J. | Stander, P. | Van Heerden, J.
Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination
2003
Knobel, D.L. (Edinburgh Univ., Midlothian (United Kingdom). Tropical Veterinary Medicine Centre) | Liebenberg, A. | Du Toit, J.T.
The epidemiology of rabies in Zimbabwe. 2. Rabies in jackals (Canis adustus and Canis mesomelas)
1999
Bingham, J. | Foggin, C.M. (Central Veterinary Laboratory, Harare (Zimbabwe)) | Wandeler, A.I. | Hill, F.W.G.
A nucleotide-specific polymerase chain reaction assay to differentiate rabies virus biotypes in South Africa
1998
Nel, L.H. (Pretoria Univ. (South Africa). Dept. of Microbiology and Plant Pathology) | Bingham, J. | Jacobs, J.A. | Jaftha, J.B.
The epidemiology of rabies in Zimbabwe. 1. Rabies in dogs (Canis familiaris)
1999
Bingham, J. | Foggin, C.M. (Central Veterinary Laboratory, Harare (Zimbabwe)) | Wandeler, A.I. | Hill, F.W.G.
Characterization and observation of animals responsible for rabies post-exposure treatment in Phnom Penh, Cambodia
1999
Reynes, J.M. (Pasteur Institute, Phnom Penh (Cambodia)) | Soares, J.L. | Keo, C. | Ong, S. | Heng, N.Y. | Vanhoye, B.
Acceptance of candidate baits by domestic dogs for delivery of oral rabies vaccines
1997
Linhart, S.B. (Georgia Univ., Athens (USA). College of Veterinary Medicine) | Baer, G.M. | Balderas Torres, J.M. | Engeman, R.M. | Flores Collins, E. | Meslin, F.X. | Schumacher, C.L. | Taweel, A.-H. | Wlodkowski, J.C.