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Efficacy of living attenuated Salmonella typhimurium vaccine in poultry
2010
Hanan M. Ibrahim | Zeinab M. Souror | N.A. Sherif | M. M. Lotfy | Elham A. El Ebiary | M. A. Makharita
The main goal of this study was to evaluate the protective efficacy of living attenuated Salmonella Typhimurium (S. Typhimurium) vaccine in poultry and to evaluate its use in control of salmonella infection in chickens. Oral vaccination of chickens within 36 hours after hatching and after 6 weeks from the first dose induced a strong humoral immune response as measured by ELISA. Challenge test was done with virulent strain of S. Typhimurium. Shedding of S. Typhimurium was detected during the first day, but after 14 days, salmonella could not be detected in the internal organs of vaccinated chickens compared with the non-vaccinated challenged chickens.
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