The prohibition of antibiotic use in edible snails obligates breeders to treat bacterial infections by different means, of which a common one is a bath in Gram-positive– and partially Gram-negative–bactericidal ethacridine lactate solution. The aim of the study was to determine the effect of bathing Cornu aspersum Müller snails in a 0.1% aqueous solution of ethacridine lactate on selected physiological parameters of haemolymph. The study included 80 snails, divided into two equal groups (study and control). The study group was subjected to bathing in ethacridine lactate and the control group to bathing in tap water. Both groups were treated daily for seven days. The number of haemocytes in the haemolymph, the activity of alanine (ALT) and aspartate (AST) aminotransferases, and the concentration of urea were determined. In the study group, after exposure to ethacridine lactate solution an increase in ALT activity, changes in the De Ritis ratio, an increase in the amount of haemocytes, and a decrease in body weight were found. No such changes were detected in the control group snails or in animals after the first bath. Multiple applications of a 0.1% ethacridine lactate bath may adversely affect Cornu aspersum Müller snails.

<p>The purpose of this experiment was to determine during experimental infection of goats the levels of total plasma protein and fibrinogen, serum aspartate aminotransferase, serum alanine aminotransferase, and direct and indirect total serum bilirrubins. Twenty healthy mongrel goats of both sexes, ten months old and with eight kilograms in body weight were utilized in this investigation. The animals were divided into two groups: group “A", control and the group "B" was inoculated intraperitoneally with five mililiters, of a culture of Leptospira interrogans serovar pomona, strain M7/87. The first blood sample was collected on the third day post infection. From the third to fifteenth day, samples were collected at four days intervals. Subsequently samples were collected at six days intervals between the sixteenth to the forty fourth day. Finally, between the forty fifth to the ninetieth day post infection, sample were collected at seven days intervals. Total and direct bilirrubin were significantly higher (P &lt; 0.05) in the infected group than in the control group. For other parameters, there was no statistically significant difference (P &lt; 0.05) between the two groups.</p> | <p>Com o objetivo de estudar os aspectos laboratoriais, através da determinação do fibrinogênio plasmátieo, proteína total plasmática, aspartato e alanina aminotransferases séricas, e bilirrubinas séricas total, direta e indireta, utilizaram-se 20 caprinos mestiços, clinicamente sadios, de ambos os sexos, com dez meses de idade e, com peso vivo médio de oito quilogramas. Os animais foram divididos aleatoriamente em dois grupos de dez: grupo "A”, controle e grupo "B". experimental. Nos animais deste último grupo foram inoculados cinco mililitros, via intraperitoneal, de cultura de Leptospira interrogans sorotipo pomona (estirpe M7/87), previamente preparada. Inicialmente, as amostras sanguíneas foram colhidas a partir do 3^º dia após inoculação, em intervalos de quatro dias, entre o 3^º e 15^º dia, passando para seis dias do 16^º ao 44^º dia, e finalmente para sete dias entre o 45^º e 93^º dia. A análise estatística revelou significância a nível de 5% para a bilirrubina total e direta, enquanto para as demais variáveis não houve diferenças significativas entre os tratamentos.</p>