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Effects of ivermectin and fenbendazole in strategic treatment of gastrointestinal nematode infections in cattle.
1990
Williams J.C. | Knox J.W. | Barras S.A. | Hawkins J.A.
Four groups of 18 beef calves each were used to evaluate effects of different treatments on parasite control and weight gains. The investigation extended from November 1986 (weaning) to October 1987. Group-1 calves were treated with ivermectin (200 micrograms/kg of body weight, SC) at approximately 6-week intervals for a total of 8 treatments; group-2 calves were given the same dosage of ivermectin by the same route of administration as group-1 calves in November, March, and July; group-3 calves were given fenbendazole paste (5 mg/kg, PO) at the same times as group-2 calves; and group-4 calves served as untreated controls with provision for ivermectin salvage treatment. All groups grazed on individual pairs of larval-contaminated, 1.6-ha pastures. Highest (P < 0.05) initial worm counts in fall tracer calves were found in group 3 (Ostertagia ostertagi and Trichostrongylus axei adults) and group 4 (O ostertagi and Haemonchus adults). Fecal egg counts of group-1 calves were low throughout the experiment and pasture larval counts remained negligible after July. Egg counts and larval counts of other groups remained higher into summer. Worm counts, including O ostertagi inhibited early fourth-stage larvae (EL4), were highest (P < 0.05) in groups-3 and -4 spring tracer calves; numbers of O ostertagi EL4 were similarly high in groups 2, 3, and 4; and T axei counts were highest (P < 0.05) in groups-3 and -4 yearlings slaughtered in spring. Liveweights of group-1 calves were greater (P < 0.05) than in other groups from March 2 to October, and by July 2, group-2 calves had a liveweight advantage over group-4 calves. Group-3 calves had the lowest rate of gain from March to July and mean liveweight of the group was less (P < 0.05) than in all other groups from April to October. Only minimal worm numbers were recovered from groups-1 or -2 calves in October. Large numbers of O ostertagi and T axei were recovered from group-4 calves and O ostertagi from group-3 calves. A few calves in groups 3 and 4, but 365 kg in group 1, 328 kg in group 2, 316 kg in group 4, and 281 kg in group 3.
Показать больше [+] Меньше [-]Controlled tests with fenbendazole in equids: Special interest on activity of multiple doses against natural infections of migrating stages of strongyles
1983
Lyons, E.T. | Drudge, J.H. | Tolliver, S.C.
Strongylus spp. and other parasites of equids (natural infections), controlled tests with fenbendazole in multiple doses at two dose levels
Показать больше [+] Меньше [-]Anthelmintic efficacy of oxibendazole in ponies: Comparison of methods
1982
Theodorides, V.J. | Nawalinski, T. | Chimes, N. | Weideman, C. | Free, S.M.
nematodes of ponies, efficacy of oxibendazole in paste formulation, 1-group critical test compared with 2-group control test
Показать больше [+] Меньше [-]Efficacy of ivermectin against inhibited larvae of Ostertagia ostertagi
1981
Williams, J.C. | Knox, J.W. | Baumann, B.A. | Snider, T.G. | Kimball, M.G.
Ostertagia ostertagi, beef cattle, acquisition of inhibited larvae during winter and spring, efficacy of ivermectin against inhibited early 4th-stage larvae of O. ostertagi and other nematodes of abomasum and intestinal tract: Louisiana
Показать больше [+] Меньше [-]A technique for the recovery of nematodes from ruminants by migration from gastro-intestinal ingesta gelled in agar: Large-scale application
1980
Van Wyk, J.A. | Gerber, H.M. | Groeneveld, H.T.
nematodes of ruminants, large scale technique for recovery of worms migrating from gastro-intestinal ingesta gelled in agar, significantly more male than female worms failed to migrate, L4 stages generally migrated more efficiently than did adult worms, some genera migrated more efficiently than others, applications for use in quantitative worm recovery such as in anthelmintic testing
Показать больше [+] Меньше [-]Efficacy of levamisole against immature and mature nematodes in goats with induced infections
1989
Coles, G.C. | Giordano, D.J. | Tritschler, J.P. II.
Anthelmintic efficacy of levamisole against induced infections with 7- and 21-day-old Haemonchus contortus, Ostertagia circumcincta, Trichostrongylus axei, and T colubriformis was evaluated as an oral drench in goats. Group 1 (n = 8) was not treated, group 2 (n = 8) was given 3.96 mg of levamisole/kg of body weight, group 3 (n = 8) was given 7.92 mg of levamisole/kg, and group 3 (n = 7) was given 11.88 mg of levamisole/kg. Efficacy against all worms was low in goats given 3.96 mg of levamisole/kg, but was high against adult H contortus (99%) and adult T colubriformis (99.7%) in goats given 7.92 mg of levamisole/kg. Although efficacy against adults of all species was high in goats given 11.88 mg of levamisole/kg, some immature worms of all species remained in the abomasa of goats.
Показать больше [+] Меньше [-]High concentration of serum gastrin immunoreactivity and abomasal mucosal hyperplasia in calves infected with Ostertagia ostertagi and/or Trichostrongylus axei
1988
Snider, T.G. | Williams, J.C. | Karns, P.A. | Markovits, J.E. | Romaire, T.L.
Parasite-free, 4-month-old-calves were inoculated with Ostertagia ostertagi and/or Trichostrongylus axei, followed 6 weeks later by inoculation with increasing doses of O ostertagi for 8 weeks in the 2 groups (n = 9) of calves that had been given O ostertagi. Gastrin immunoreactivity concentration in serum was measured before and after infection and was correlated with changes in mucosal thickness. Gastrin immunoreactivity concentration in preinoculation control sera ranged from 95.2 to 287.1 pg/ml, and increased values were measured in all parasitized calves after 15 weeks. Significantly (P < 0.05) increased serum gastrin immunoreactivity concentration compared with the preinfection value, was found in calves infected with O ostertagi or T axei, and highly significant (P < 0.01) values were observed in calves infected with both parasites. Abomasal mucosal hyperplasia was observed in all parasitized calves; increased mucosal thickness and mucosal cross-sectional area were most prominent in calves infected with O ostertagi and T axei.
Показать больше [+] Меньше [-]Anthelmintic efficacy of fenbendazole against the bovine hookworm Bunostomum phlebotomum
1983
Williams, J.C. | Baumann, B.A. | Hoerner, T.J. | Knox, J.W. | Snider, T.G.
Bunostomum phlebotomum experimental infection of beef calves superimposed upon naturally occurring gastrointestinal nematode infections, fenbendazole anthelmintic efficacy tested
Показать больше [+] Меньше [-]Further tests of activity of levamisole on Ostertagia ostertagi in dairy calves with notes on overwinter survival of gastrointestinal helminths on pasture
1983
Lyons, E.T. | Drudge, J.H. | Tolliver, S.C. | Hemken, R.W. | Button, F.S.,jr
mature Ostertagia ostertagi and immature Ostertagia spp. in naturally infected dairy calves, activity of levamisole; overwinter survival on pasture of gastrointestinal helminth free-living stages as found in necropsy of previously helminth free calves placed on pasture in April: Kentucky
Показать больше [+] Меньше [-]Evaluation of albendazole in cattle naturally infected with nematodes
1982
Todd, K.S., jr | Mansfield, M.E.
nematodes, calves, albendazole evaluated
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