Canine oral papillomatosis is a contagious and spontaneously regressing benign neoplastic disease of young dogs caused by canine oral papillomavirus. Six dogs of different breeds aged between 1-3 years were presented to Veterinary Clinical Complex with the history of wart like lesions in different parts of the oral cavity. Under Xylazine sedation and 10 % Lignocaine spray representative biopsy sample of wart was surgically excised. Autogenous vaccine was developed and mixed with formalin solution to in activate the virus. Dogs were subjected to inj. Autovaccine 1 ml through subcutaneous route once in a week for 5 weeks. Warts were completely regressed within 4 weeks period after autoimmune therapy. There was no recurrence of papillomatosis among the treated dogs during the follow-up period of 6 months and no adverse effects were recorded.

A primiparous Holstein Friesian crossbred cow was brought to VCC, VC&RI Namakkal with ventral swelling. Based on rectal examination and abdominal palpation it was diagnosed as right sided uterine torsion with prepubic tendon rupture. After the fetal delivery by caesarean section and proper postoperative care is given for a period of 10 days, life of the dam was saved.

Recently calved Jersey crossbred primiparous cow was presented with history of in appetence and scanty voiding of dung for past 3 days. On physical examination vital parameters were within normal range. On per rectal examination, there was distended caecum from the pelvic inlet which extended cranially. Per rectal examination revealed distension of caecum which was extended cranially. Simultaneous auscultation and percussion on the right upper flank revealed clear metallic ping sound which extended up to 11th intercostal space on first day. Transabdominal ultrasonographic examination revealed thick semicircular echogenic caecal wall and contents on mid upper flank, extended up to 11th intercostal space. Bethanechol 0.07 mg/kg SID orally along with parenteral fluid therapy was given for 3 days. On fourth day after initiation of therapy the animal voided dung normally and recovered uneventfully.

A nine months male cat was presented with the history of itching and scratching over the face, ears and forelimb since a month. On physical examination alopecia, scales, crusty, thick, wrinkled and leathery lesions were found on the face and ears. All the vitals were within the normal range. Microscopic examination of the skin scrapping revealed Notoedres cati. Further history also revealed the presence of pruritus and cutaneous lesions on the shoulder and arm region of the owner. The cat was treated with Inj.Ivermectin @200 µg/kg along with topical application of sulphur (10%).

Biometry and follicular parameters of porcine ovaries sourced from organized and unorganized-slaughterhouses and relative comparison of oocyte retrieval methods, namely aspiration and slicing, are reported in the present study. Average length and width of the ovaries, and numbers of surface and cystic follicles were higher in ovaries sourced from organized slaughterhouses. Average number of oocytes recovered per ovary by slicing (12.93±1.49) was significantly higher (P<0.01) than aspiration (6.36±1.02). However, aspiration yielded higher percentage (65.21±5.71) of good quality oocytes (A) (P<0.01) suitable for upstream applications of assisted reproductive technologies (ART). Further, our study reveals that ovaries sourced from unorganized slaughterhouses can also be used for ART, and use of aspiration method may yield better quality oocytes.

Oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage in a variety of liver disorders. Hence, there is a great demand for the development of agents with potent antioxidant effect. The aim of the present investigation is to evaluate the efficacy of raw and nanoforms of resveratrol and silibinin as a hepatoprotective and an antioxidant against diethylnitrosamine induced hepatocellular damage. 0.01% diethylnitrosamine administration to rats resulted in significantly elevated levels of lipid peroxidation (LPO) and decreased levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GSH) and total protein (TP) in the liver tissue. Post-treatment with the nano resveratrol (50 mg/kg), nano silibinin (50 mg/kg), raw resveratrol (50 mg/kg), raw silibinin (50 mg/kg) orally for 30 days significantly reversed the diethylnitrosamine induced alterations in the liver tissue and offered almost complete protection. The results from the present study indicate that both nano forms exhibit good hepatoprotective and antioxidant potential against diethylnitrosamine induced hepatocellular damage in rats as compared to raw forms.

Leptospirosis is one of the most important zoonotic disease caused by the pathogenic leptospires Leptospira interrogans. In this study, four pathogenic Leptospira serovars were selected based on the seroprevalence data, their LPS extracted, assessed for its purity and seroreactivity and processed for the determining the fatty acid profiles. The average concentration of the LPS extracted from the cultures across the serovars was 742.75+19.4 µg/ml with the polysaccharides contributing to 77.2 % of the LPS (573.6+18.01 µg/ml). The common fatty acids that were present in all the four serovars included butyric acid (C4:0), capric acid (C10:0), palmitoleic acid (C16:0),  eicosapentaenoic acid (C20:5n3) and docosapentaenoic acid (C22:6n3). The heptadecanoic acid (C17:1) was present in serovars australis and autumnalis; pentadecanoic acid (C15:0) in canicola and hardjo serovars and caproic acid (C6:0) in the serovars autumnalis and canicola. The fatty acid eicosatrinoic acid (C20:3n3) was unique to the serovar autumnalis and the myristic (C13:0) and docosadienoic acid (C22:2) being unique to the serovar hardjo. Future studies to understand the fatty acid profile of the other common pathogenic circulating Leptospira LPS will add scientific evidence to the minor cross-reactivity observed across the serovars in MAT.

Mammary tumours are considered as the most important neoplasms in dogs especially in sexually intact female dogs. Prognosis is directly associated with various factors such as tumour size, metastases, involvement of lymph node, tumour type and grade. Recently, tumour microenvironment (TME) has gained huge importance and proved to be a key regulator of breast cancer's biologic behaviour, according to mounting data. The capacity of extracellular matrix components like collagen to alter their intrinsic structure and alignment aids in tumour invasion and metastasis. We present a case study of 25 canine mammary tumours (CMTs), where the stroma associated with the malignancy was specifically considered while histomorphologically analysing the tumours. The majority of the tumours were malignant (96 per cent) and one was identified to be benign. Simple carcinomas made up the majority of tumours, followed by mixed types. Cancer associated stroma was assessed by routine H and E staining and additionally by performing immunohistochemistry technique with anti-cytokeratin antibody to access the relative abundance of neoplastic epithelial cells. Special stains such as Picrosirius red, Masson’s trichrome and Herovici were employed to demonstrate the desmoplastic stromal reaction and varying grades of collagen could be observed in the stroma of different tumours. The extent of fibroplasia was found to be directly proportional to the grade and size of tumour. Thus, results of the present study indicated that the cancer associated stroma significantly in fluence the CMT progression and clinical outcome.

A study was conducted in Murrah buffaloes belonging to Livestock Farm Complex of Veterinary College and Research Institute, Orathanadu, located in cauvery delta region to document the effect of heat ameliorative measures on physiological responses during summer. Twenty four buffaloes were selected and divided into four treatment groups of 6 animals per group. All the animals were maintained under standard managemental conditions with wallowing facility. The treatment group (T1) was control, animals in T2 were provided with cooling jacket, animals in T3 were supplemented with probiotics (Saccharomyces cerevisiae) and T4 animals received probiotics (Saccharomyces cerevisiae) and were provided cooling jacket. Physiological parameters viz., respiratory rate, pulse rate and rectal temperature were recorded during the summer season (March 2022 to May 2022) at weekly intervals in animals of all the treatment groups. Measurements were made when animals were at rest and after the exposure to sun light at 9 am and 2 pm respectively. From results it was concluded that the heat ameliorative measures given to the different groups of animals decreased the respiratory rate, pulse rate and rectal temperature during summer.

Examination of gastro intestinal tract of 20 carcasses of backyard poultry revealed mucoid material in the lumen of the proventriculus and gizzard. The mucosa of proventriculus and gizzard were thickened. Peeling of the horny gizzard cuticle layer revealed the presence of Cheilospirura hamulosa on the sub-mucosal and muscular surface. The lumen of different parts of the gastrointestinal tract contained tenacious muco-sanguineous content. Caeca was completely filled with tarry red coloured content mixed with Subulura brumpti.