Water pollution is one of the main challenges and water crises, which has caused the existing water resources to be unusable due to contamination. To understand the determinants of the distribution and abundance of antibiotic resistance genes (ARGs), we examined the distribution of 22 ARGs in relation to habitat type, heavy metal pollution and antibiotics concentration across six lakes and wetlands of Iran. The concentration of 13 heavy metals was determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES) by Thermo Electron Corporation, and five antibiotics by online enrichment and triple-quadrupole LC-MS/MS were investigated. We further performed a global meta-analysis to evaluate the distribution of ARGs across global lakes compared with our studied lakes. While habitat type effect was negligible, we found a strong correlation between waste discharge into the lakes and the abundance of ARGs. The ARGs abundance showed stronger correlation with the concentration of heavy metals, such as Vanadium, than with that of antibiotics. Our meta-analysis also confirmed that overuse of antibiotics and discharge of heavy metals in the studied lakes. These data point to an increase in the distribution of ARGs among bacteria and their increasing resistance to various antibiotics, implying the susceptibility of aquatic environment to industrial pollution.

The solar ultraviolet radiation (UVR) at national, provincial and county levels in Iran during 2005–2019 were determined based on Ozone Monitoring Instrument (OMI) dataset. The temporal (annual and monthly) trends and spatial distributions of the UVR in terms of erythemally weighted daily dose (EDD), erythemally weighted irradiance at local solar noon time (EDR), and UV index and the major factors influencing the spatiotemporal trends were analyzed. The population-weighted average values of EDD, EDR, and UV index in Iran were respectively 3631 J/m², 176.3 mW/m², 7.1 in 2005 and rose by 0.22% per year to 3744 J/m², 181.7 mW/m², and 7.3, respectively in 2019, but the annual trend was not statistically significant. The EDD in Iran during the study period exhibited the highest monthly average value in June (6339 J/m²) and the lowest one in December (1263 J/m²). The solar UVA/UVB ratios at the national level during 2005–2019 were considerably lower in summer. The EDD provincial average values in the study period were in the range of 2717 (Gilan) to 4424 J/m² (Fars). The spatiotemporal variations of the solar UVR parameters were well described by the linear models as a function of cloud optical thickness (COT), ozone column amount, surface albedo, latitude, and altitude (R² > 0.961, p value < 0.001) and the temporal changes of the solar UVR parameters were mainly caused by the COT. The results indicated that non-burning exposure to solar UVR in summer can be more efficient for vitamin D synthesis due to higher contribution of UVB in the solar UVR. The spatial distributions and temporal trends should be considered to determine the optimal duration, time and condition of exposure to the solar UVR for the public and occupational training and public health measures.

Elevated toxins in soybeans extensively threaten Asian residents and over one billion vegetarians worldwide. An integrated dataset of toxic trace metal(loid)s especially cadmium (Cd) analysis in soybean grain samples (n = 5217) from 12 countries/regions of origin was compiled for risk analysis. Worldwide grain Cd averaged 0.093 mg kg⁻¹, but mean values varied 16-fold between regions, with South China (0.32 mg kg⁻¹) > Argentina (0.15 mg kg⁻¹) = German (0.13 mg kg⁻¹) > Japan (0.11 mg kg⁻¹) > the United States (0.064 mg kg⁻¹) > Central-North China (0.020–0.60 mg kg⁻¹) ≥ Iran (0.042 mg kg⁻¹) = Brazil (0.023 mg kg⁻¹) = South Korea (0.020 mg kg⁻¹). Regression analysis suggested widespread contamination and acidic soil features significantly contributed the elevated food Cd contamination worldwide. Arsenic (As) and lead (Pb) are also of concern because excessive levels were often observed in grains. Given that soil Cd bioavailability is generally low in alkaline pH ranges, the feasibility of producing safe food from contaminated land was investigated by greenhouse experiments with one low-Cd soybean cultivar grown on 20 contaminated calcareous soils. Equilibrium-based approaches i.e., 0.01 M CaCl₂ and in-situ porewater extractions, and diffusion-based diffusive gradients in thin-films technique were used to determine the plant-available fractions of soil metal(loid)s to explain the bioaccumulation variation. The results suggested that soybean grains bioaccumulated mean 0.76 mg Cd kg⁻¹, ranging from 0.16 to 2.1 mg kg⁻¹, whereas As and Pb bioaccumulation was low. Cadmium accumulation was closely correlated with plant-available Cd fractions especially the 0.01 M CaCl₂-extractable Cd, but negatively correlated with soil pH. Even in the alkaline pH range, a slight decrease of soil pH would increase grain Cd significantly. Study region and those arable lands that have similar soil conditions are not recommended for growing soybean unless novel remediation strategies are developed.

Ambient carbon monoxide (CO) and particulate matters (PMs) are two important air pollutants in urban areas with known impacts on fetuses. Hence, this study measured some biochemistry factors of 200 neonates with birth dates from January 19 to October 12, 2020, including the birth weight and height and the serum levels of ALT, AST, ALP, GGT, and TSH. The Support Vector Machine-fitted land-use regression approach was used to predict the spatio-temporal variability of intra-urban PM 2.5 and CO concentrations by month during the pregnancy period of the cases employing 5 variables of Digital Elevation Model (DEM), slope, and distance from Compressed Natural Gas (CNG) stations, Bus Rapid Transit (BRT) stations, and mines and industries. Spearman correlation analysis (p < 0.05) was performed between the neonate indices and mean monthly PM 2.5 and CO concentrations at the exact residential address of maternal cases and their nearby areas in 250, 500, 1000, 1500, and 2000 m-radius buffer rings. All modeling efforts succeeded in predicting CO and PM 2.5 levels with acceptable adjusted r² values. Northern Isfahan had relatively higher CO and PM 2.5 concentrations due to its adjacency to low-vegetated open lands and its high traffic load as compared to southern areas. The correlation results between the neonate biochemistry indices and mean PM 2.5 and CO concentrations were mostly positive in most buffer rings, especially in the >500 m-radius buffer rings for PM 2.5 and in the 2000 m-radius rings for CO. Although the correlation results of PM 2.5 followed a detectable trend in the buffer rings, the associations between CO and the neonate biochemistry indices differed significantly between the buffer rings. Results showed that increasing mean monthly concentration of CO and PM 2.5 may stimulate further production of liver enzymes while decreasing the birth weight and height.

Metal(loid)s (MLs) with natural or anthropogenic sources may cause adverse health effects in children. This study aimed to compare the childhood exposure to ΣMLs (essential, non-essential and toxic) in an industrial and an urban area in Southwest Iran using toenail tissue as a biomarker. The present study was carried out with school children in the age range of 7–12 years, who were living in an industrial area in the petrochemical and gas area (PGA) of the Central District of Asaluyeh County and in an urban area (UA) located in the Kaki District. A total of 270 boys and girls were recruited in January to April 2019. The ICP-MS was used for determination of the studied MLs. A multi-linear regression model was constructed to assess the effect of residence area on toenail ML levels. A significantly higher level of ΣMLs in toenail from the PGA was observed compared to the level in the UA (8.839 vs. 7.081 μg/g, β = -0.169 and p < 0.05). However, all of the 15 MLs studied were detected in the toenail samples from both study sites. Significant differences for the mean Cr (β = −0.563), Fe (β = −0.968), Mn (β = −0.501), Ni (β = −0.306), and Pb (β = −0.377) levels were found between toenail samples from the study areas (p < 0.05), with higher levels in the PGA. The results of this study suggest that children in industrial area are prone to a greater risk for ML exposures compared with those living in a non-industrial urban area.

PM₂.₅-bound PAHs were analyzed in a total of 135 daily samples collected during four seasons from 2018 to 2019, at three urban sites in Tehran, Iran. This study aims to investigate spatio-temporal variations, source apportionment, potential local and regional sources contributions and lung cancer risks associated with the 16 US EPA priority PAHs. PM₂.₅ concentrations ranged from 43.8 to 80.3 μg m⁻³ with the highest concentrations observed in summer. Total PAHs (TPAHs) concentrations ranged between 24.6 and 38.9 ng m⁻³. Autumn period exhibited the highest average concentration (48.3 ng m⁻³) followed by winter (29.5 ng m⁻³), spring (25.9 ng m⁻³) and summer (16.1 ng m⁻³). Five PAHs sources were identified by positive matrix factorization (PMF) analysis: diesel exhaust, unburned petroleum-petrogenic, industrial, gasoline exhaust and coal/biomass combustion-natural gas emissions, accounting for 22.3%, 15.6%, 7.5%, 30.9%, and 23.6% of TPAHs, respectively. Site-specific bivariate polar (BP) and conditional bivariate probability function (CBPF) plots were computed to assess PM₂.₅ and TPAHs local source locations. CBPF pointed out that TPHAs sources are likely of local origin, showing the highest probability close to the sampling sites associated with low wind speed (<5 m s⁻¹). The potential source contribution function (PSCF) and the concentration weighted trajectory (CWT) models were applied to investigate the long-range transport of PM₂.₅ and TPAHs. In addition to local sources contributions, Eastern areas were highly related to long-distance transport of PM₂.₅ and the Western areas showed the highest contribution of the total, medium molecular weight (MMW) (4 rings) and high molecular weight (HMW) (5–6 rings) PAHs. The upper bound of incremental lifetime cancer risk (ILCR) via inhalation exposure to PM₂.₅-bound PAHs was at a moderate risk level (3.14 × 10⁻⁴ to 6.17 × 10⁻⁴).

Swift degradation of the coral reef ecosystems urges the need to identify the reef decline drivers. Due to their widespread use, bioaccumulative and toxic characteristics, chlorinated organic compounds, such as chlorinated paraffins (CPs), are regarded as specific pollutants of concern. Yet little is known about the occurrence of CPs in the coral reef ecosystems. This study focuses on the short-chain chlorinated paraffins (SCCPs) and medium-chain chlorinated paraffins (MCCPs). Their distribution and congener pattern were investigated in the water-SPM-sediment system and in the corals of the Larak coral reef for the first time. Chlorinated paraffins were detected in all the coral species. Their total loadings ranged from 42.1 to 178 ng g⁻¹ dw in coral tissue, from 6.0 to 144 ng g⁻¹dw in the skeleton, and from 55.0 to 240 ng g⁻¹dw in zooxanthellae. Soft corals were found to accumulate more CPs than Scleractinian corals. Zooxanthellae and mucus accumulated more CPs than tissue and skeleton. In most cases, congener group patterns were dominated by C₁₃ (for SCCPs) and C₁₇ (MCCPs) groups, respectively. The congener patterns of CPs altered to some extent between mucus and the remaining coral compartments. High loadings of CPs were detected in the skeleton of the bleached corals. Moreover, a significant negative correlation between the levels of CPs and the symbiodinium density was observed.

In this work, a sand and dust storm vulnerability mapping (SDS-VM) approach is developed to model the vulnerability of urban blocks to SDS using GIS spatial analysis and a range of geographical data. The SDS-VM was carried out in Ahvaz, IRAN, representing one of the most dust-polluted cities in West Asia. Here, vulnerability is defined as a function of three components: exposure, sensitivity, and adaptive capacity of the people in the city blocks to sand and dust storms. These components were formulated into measurable indicators (i.e. GIS layers) including: PM₂.₅, wind speed, distance from dust emission sources, demographic statistics (age, gender, family size, education level), number of building floors, building age, land surface temperature (LST), land use, percentage of literate population, distance from health services, distance from city facilities (city center, shopping centers), distance from infrastructure (public transportation, main roads and highways), distance from parks and green spaces, and green area per capita. The components and the indicators were weighted using analytical hierarchy process (AHP). Different levels of risks for the components and the indicators were defined using ordered weighted averaging (OWA). Urban SDS vulnerability maps at different risk levels were generated through spatial multi-criteria data analysis procedure. Vulnerability maps, with different risk levels, were validated against field-collected data of 781 patients hospitalized for dust-related diseases (i.e. respiratory, cardiovascular, and skin). Results showed that (i) SDS vulnerability map, obtained from the developed methodology, gives an overall accuracy of 79%; (ii); regions 1 and 5 of Ahvaz are recognized with the highest and lowest vulnerabilities to SDS, respectively; and (iii) ORness equal to 0 (very low risk) is the optimum SDS-VM risk level for decision-making to mitigate the harmful impacts of SDS in the deposition areas of Ahvaz city.

The presence of polycyclic aromatic hydrocarbons (PAHs) in the fetal environment is a high-priority concern due to the fetus being more sensitive than adults to these ubiquitous xenobiotics. The aim of the present study was to compare the maternal and fetal serum levels of ΣPAHs and their effects on fetal growth in an industrial and an urban area in Southwest Iran. The industrial area was the petrochemical and gas area (PGA) of the Central District of Asaluyeh County and the urban area (UA) was the Central District of Bushehr County, Ninety-nine maternal serum (MS) and 99 cord serum (CS) samples from the PGA and 100 MS and 100 CS samples from the UA were collected during May 2018 to February 2019. The mean concentrations of ΣPAHs were significantly (p < 0.05) higher in the PGA than the UA in both MS (157.71 vs. 93.56 μg/L) and CS (155.28 vs. 93.19 μg/L) samples. Naphthalene (NAP) was the predominant PAH detected in all the studied samples. Significant negative associations were found between birth weight and anthracene (ANT) level in MS (β = −22.917, p = 0.032; weight decrement = 22.917 g for a 1 μg/L increase in ANT); head circumference and chrysene (CHR) level in MS (β = −0.206, p = 0.023; head circumference decrement = 0.206 cm for a 1 μg/L increase in CHR); and birth height and NAP level in CS (β = −0.20, p = 0.005; height decrement = 0.20 cm for a 1 μg/L increase in NAP). Maternal diet had a significant effect on the serum levels of PAHs. The results of this study showed that transmission of PAHs from mother to fetus through the cord blood is an important issue and mothers who live in industrial areas and consume PAH-containing foodstuffs, and their fetuses, are more at risk than those living in a non-industrial urban area.

The present study aimed to reveal correlations between environmental events and geochemistry variation and ecological risks of the coastal Tajan River. Sediment quality indices (Cf, Cd, Er, and RI) were applied to achieve the research objectives based on the concentration of toxic metals (As, Cd, Cr, Cu, Ni, Pb, Zn). The probably effective level is based on the concentration of As, Cr, and Ni observed. The coastal zone and the urban sector of the river have experienced a moderate ecological risk since 1975, especially during wet seasons (1988–1997) with a mean sedimentation rate of 2 cm/year. A significant correlation (r=0.439–0.633, p-values < 0.0001) between the toxic metal concentration and the Caspian Sea level fluctuation was obtained. The lowest concentration of toxic metals coincided with the high stand water level. Management practices recommend controlling toxic metals (As, Cd, Ni, Cr, Pb) from the sources and dredging of retention pounds along the Tajan River.