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A review on occurrence of emerging pollutants in waters of the MENA region
2021
Haddaoui, I. | Mateo-Sagasta, Javier
Farmed tilapia as an exposure route to microcystins in Zaria-Nigeria: A seasonal investigation
2021
Chia, Mathias Ahii | Abdulwahab, Rabiu | Ameh, Ilu | Balogun, J Kolawole | Auta, Jehu
Several studies have reported the contamination of farmed fish by microcystins, however, alternations in levels of contamination resulting from seasonal changes are infrequently described. This investigation is focused on the seasonal accumulation of microcystins in farmed Nile Tilapia muscle tissue across three farms located in Zaria, Nigeria, as a means of assessing the health risks associated with the consumption of contaminated fish. Total microcystins and cyanobacteria content, respectively, in muscle tissue and gut of tilapia varied, seasonally in the farms. Microcystin levels were higher in fish tissues analyzed in the dry season than the rainy season at Nagoyi and Danlami ponds. Correlating with the levels of microcystins found in fish tissues, the highest dissolved microcystins levels in all the fish farms occurred in the dry season, where the Bal and Kol fish farm had the highest concentration (0.265 ± 0.038 μgL⁻¹). Gut analysis of fish obtained from the ponds, revealed a predominance of Microcystis spp. among other cyanobacteria. Estimation of total daily intake of consumed contaminated Nile tilapia muscles reveal values exceeding WHO recommended (0.04 μg kg⁻¹ body weight) total daily intake of MC-LR. Consumption of tilapia from Danlami pond presented the greatest risk with a value of 0.093 μg kg⁻¹ total daily intake. Results of the present study necessitate the implementation of legislation and monitoring programs for microcystins and other cyanobacteria contaminants of fish obtained from farms and other sources in Zaria and indeed several other African countries.
Показать больше [+] Меньше [-]Metagenomic insights into the antibiotic resistome of mangrove sediments and their association to socioeconomic status
2021
Imchen, Madangchanok | Kumavath, Ranjith
Mangrove sediments are prone to anthropogenic activities that could enrich antibiotics resistance genes (ARGs). The emergence and dissemination of ARGs are of serious concern to public health worldwide. Therefore, a comprehensive resistome analysis of global mangrove sediment is of paramount importance. In this study, we have implemented a deep machine learning approach to analyze the resistome of mangrove sediments from Brazil, China, Saudi Arabia, India, and Malaysia. Geography (RANOSIM = 39.26%; p < 0.005) as well as human intervention (RANOSIM = 16.92%; p < 0.005) influenced the ARG diversity. ARG diversity was also inversely correlated to the human development index (HDI) of the host country (R = −0.53; p < 0.05) rather than antibiotics consumption (p > 0.05). Several genes including multidrug efflux pumps were significantly (p < 0.05) enriched in the sites with human intervention. Resistome was consistently dominated by rpoB2 (19.26 ± 0.01%), multidrug ABC transporter (10.40 ± 0.23%), macB (8.84 ± 0.36n%), tetA (4.13 ± 0.35%), mexF (3.26 ± 0.19%), CpxR (2.93 ± 0.2%), bcrA (2.38 ± 0.24%), acrB (2.37 ± 0.18%), mexW (2.19 ± 0.17%), and vanR (1.99 ± 0.11%). Besides, mobile ARGs such as vanA, tet(48), mcr, and tetX were also detected in the mangrove sediments. Comparative analysis against terrestrial and ocean resistomes showed that the ocean ecosystem harbored the lowest ARG diversity (Chao1 = 71.12) followed by mangroves (Chao1 = 258.07) and terrestrial ecosystem (Chao1 = 294.07). ARG subtypes such as abeS and qacG were detected exclusively in ocean datasets. Likewise, rpoB2, multidrug ABC transporter, and macB, detected in mangrove and terrestrial datasets, were not detected in the ocean datasets. This study shows that the socioeconomic factors strongly determine the antibiotic resistome in the mangrove. Direct anthropogenic intervention in the mangrove environment also enriches antibiotic resistome.
Показать больше [+] Меньше [-]Atmospheric mercury pollution caused by fluorescent lamp manufacturing and the associated human health risk in a large industrial and commercial city
2021
Luo, Qing | Ren, Yuxuan | Sun, Zehang | Li, Yu | Li, Bing | Yang, Sen | Zhang, Wanpeng | Hu, Yuanan | Cheng, Hefa
Although already eliminated in most industrial processes, mercury, as an essential ingredient in all energy-efficient lighting technologies, is still used in fluorescent lamp manufacturing. This study was conducted to investigate the atmospheric pollution caused by fluorescent lamp production and assess the associated public health risk in a large industrial and commercial city of south China, Zhongshan, which is a major production hub of lighting products. Concentrations of total gaseous mercury (TGM) in the atmosphere were measured over a total of 342 sites in the industrial, commercial, and residential areas. The average levels of TGM in the industrial, commercial, and residential areas prior to the landing of a typhoon were 12 ± 11, 3.6 ± 2.1, and 2.7 ± 1.3 ng⋅m⁻³, respectively. TGM concentrations in the industrial areas exhibited significant diurnal variation, with levels in the working hours being much higher than those in the non-working hours, which indicates that the high atmospheric mercury concentrations were contributed by local emissions, instead of regional transport. Most fluorescent lamp manufacturing activities in the city were shut down during a typhoon event, which resulted in a significant reduction in the average TGM level (down to 1.6 ± 1.8 ng⋅m⁻³) and rendered the difference in the average TGM levels in the industrial areas no longer significant between the working and non-working hours. Elevated TGM levels (up to 49 ng⋅m⁻³) were found near clusters of small-scale fluorescent lamp workshops in both industrial and commercial areas, which is indicative of significant emissions of mercury vapor resulting from obsolete equipment and production technologies. No significant non-carcinogenic risk was found for the general residents in the sampling area over the study period, while the risk for the workers in the fluorescent lamp manufacturing facilities and workshops could be higher. These findings indicate that fluorescent lamp manufacturing in the developing countries is a major source of atmospheric mercury.
Показать больше [+] Меньше [-]Occurrence of pyrethroids in the atmosphere of urban areas of Southeastern Brazil: Inhalation exposure and health risk assessment
2021
Guida, Yago | Pozo, Karla | Carvalho, Gabriel Oliveira de | Capella, Raquel | Targino, Admir Créso | Torres, João Paulo Machado | Meire, Rodrigo Ornellas
The occurrence of organochlorine pesticides (OCPs) used decades ago for vector control in urban areas is still reported as a threat to human health. Pyrethroids emerged as a replacement for OCPs in sanitary campaigns and are currently the main insecticides used for vector control worldwide, with prominent use as agricultural and household insecticides, for veterinary and gardening purposes, and as wood preservative. This study aimed to assess the occurrence, seasonal variation, and potential sources of pyrethroids in ambient air of two urban regions of Southeastern Brazil, along with the potential health risks to local populations via inhalation exposure. Pyrethroids were sampled by polyurethane foam passive air samplers and their concentrations were determined by gas chromatography coupled with electron capture negative ionization mass spectrometry (GC/ECNI-MS). Atmospheric pyrethroid concentrations (hereinafter reported in pg m⁻³) were considerably higher than those reported by previous studies worldwide. Cypermethrin (median: 2446; range: 461–15 125) and permethrin (655; 19–10 328) accounted for 95% of the total measured pyrethroids in ambient air. The remaining fraction comprised smaller amounts of bifenthrin (46; <limit of detection (LOD)–5171), deltamethrin (58; <LOD–564), phenothrin (7; <LOD–22) and fenvalerate (0.3; <LOD–3). Bifenthrin, deltamethrin and permethrin were linked to local sources, while cypermethrin, fenvalerate and phenothrin had more prominent regional contributions. In broad terms, most pyrethroids showed no clear seasonal trend. The concentrations and hazard quotients (HQs) showed the following order of occurrence and magnitude: urban > urban-industrial > background areas. HQs increased with decreasing age group, but deterministic and probabilistic estimates did not identify direct health risks for any group. Nevertheless, since only inhalation exposure was considered in this work, other pathways should be investigated to provide a more comprehensive risk assessment of the human exposure to pyrethroids.
Показать больше [+] Меньше [-]The direct and indirect effects of copper on vector-borne disease dynamics
2021
Neff, Erik | Dharmarajan, Guha
Metal pollution is a growing concern that affects the health of humans and animals globally. Copper is an essential insect micronutrient required for respiration, pigmentation and oxidative stress protection but can also act as a potentially toxic trace element. While several studies have focused on the negative fitness effects of copper on the aquatic larvae of mosquitoes, the effects of larval copper exposure on adult mosquito fitness (i.e., survival and fecundity) and their ability to transmit parasites (i.e., vector competence) remains unclear. Here, using a well-studied model vector-parasite system, the mosquito Aedes aegypti and parasite Dirofilaria immitis, we show that sublethal copper exposure in larval mosquitoes alters adult female fecundity and vector competence. Specifically, mosquitoes exposed to copper had a hormetic fecundity response and mosquitoes exposed to 600 μg/L of copper had significantly fewer infective parasite larvae than control mosquitoes not exposed to copper. Thus, exposure of mosquito larvae to copper levels far below EPA-mandated safe drinking water limits (1300 μg/L) can impact vector-borne disease dynamics not only by reducing mosquito abundance (through increased larval mortality), but also by reducing parasite transmission risk. Our results also demonstrated that larval copper is retained through metamorphosis to adulthood in mosquitoes, indicating that these insects could transfer copper from aquatic to terrestrial foodwebs, especially in urban areas where they are abundant. To our knowledge this is the first study to directly link metal exposure with vector competence (i.e., ability to transmit parasites) in any vector-parasite system. Additionally, it also demonstrates unequivocally that mosquitoes can transfer contaminants from aquatic to terrestrial ecosystems. These results have broad implications for public health because they directly linking contaminants and vector-borne disease dynamics, as well as linking mosquitoes and contaminant dynamics.
Показать больше [+] Меньше [-]Transition in air pollution, disease burden and health cost in China: A comparative study of long-term and short-term exposure
2021
Ambient air pollution is one of the leading environmental risk factors to human health, largely offsetting economic growth. This study evaluated health burden and cost associated with the short-term and long-term exposure of major air pollutants (fine particulate matter [PM₂.₅] and ozone [O₃]) during 2013–2018. We developed a database of gridded daily and annual PM₂.₅ and O₃ exposure in China at 15 km × 15 km resolution. Then, we estimated the age- and cause-specific premature deaths and quantified related health damage with an age-adjusted value of statistical life (VSL) measure. The health cost estimated in this study captured direct cost, indirect cost and intangible cost of the premature death attributable to ambient PM₂.₅ and O₃. We found that the national premature deaths attributable to long-term and short-term exposure to PM₂.₅ decreased by 15% and 59%, whereas the national premature deaths attributable to long-term and short-term exposure to O₃ increased by 36% and 94%. Despite a 15% reduction of attributable deaths, the health cost attributable to long-term exposure to PM₂.₅ did not change significantly as a result of GDP growth and population aging. On the other hand, the long-term O₃ related health cost in 2018 doubled that in 2013. Our study suggests that while premature deaths fell as a result of China’s clean air actions, the health costs of air pollution remained high. The growing trends of O₃ highlighted the needs for strategies to reduce both PM₂.₅ and O₃ emissions, for the sake of public health and social well-being in China.
Показать больше [+] Меньше [-]Effluent decontamination by the ibuprofen-mineralizing strain, Sphingopyxis granuli RW412: Metabolic processes
2021
The high global consumption of ibuprofen and its limited elimination by wastewater treatment plants (WWTPs), has led to the contamination of aquatic systems by this common analgesic and its metabolites. The potentially negative environmental and public health effects of this emerging contaminant have raised concerns, driving the demand for treatment technologies. The implementation of bacteria which mineralize organic contaminants in biopurification systems used to decontaminate water or directly in processes in WWTPs, is a cheap and sustainable means for complete elimination before release into the environment. In this work, an ibuprofen-mineralizing bacterial strain isolated from sediments of the River Elbe was characterized and assayed to remediate different ibuprofen-polluted media. Strain RW412, which was identified as Sphingopyxis granuli, has a 4.48 Mb genome which includes plasmid sequences which harbor the ipf genes that encode the first steps of ibuprofen mineralization. Here, we confirm that these genes encode enzymes which initiate CoA ligation to ibuprofen, followed by aromatic ring activation by a dioxygenase and retroaldol cleavage to unequivocally produce 4-isobutylcatechol and propionyl-CoA which then undergo further degradation. In liquid mineral salts medium, the strain eliminated more than 2 mM ibuprofen within 74 h with a generation time of 16 h. Upon inoculation into biopurification systems, it eliminated repeated doses of ibuprofen within a few days. Furthermore, in these systems the presence of RW412 avoided the accumulation of ibuprofen metabolites. In ibuprofen-spiked effluent from a municipal WWTP, ibuprofen removal by this strain was 7 times faster than by the indigenous microbiota. These results suggest that this strain can persist and remain active under environmentally relevant conditions, and may be a useful innovation to eliminate this emerging contaminant from urban wastewater treatment systems.
Показать больше [+] Меньше [-]Valorisation of medical waste through pyrolysis for a cleaner environment: Progress and challenges
2021
Su, Guangcan | Ong, Hwai Chyuan | Ibrahim, Shaliza | Fattah, I. M Rizwanul | Mofijur, M. | Chong, Cheng Tung
The COVID-19 pandemic has exerted great shocks and challenges to the environment, society and economy. Simultaneously, an intractable issue appeared: a considerable number of hazardous medical wastes have been generated from the hospitals, clinics, and other health care facilities, constituting a serious threat to public health and environmental sustainability without proper management. Traditional disposal methods like incineration, landfill and autoclaving are unable to reduce environmental burden due to the issues such as toxic gas release, large land occupation, and unsustainability. While the application of clean and safe pyrolysis technology on the medical wastes treatment to produce high-grade bioproducts has the potential to alleviate the situation. Besides, medical wastes are excellent and ideal raw materials, which possess high hydrogen, carbon content and heating value. Consequently, pyrolysis of medical wastes can deal with wastes and generate valuable products like bio-oil and biochar. Consequently, this paper presents a critical and comprehensive review of the pyrolysis of medical wastes. It demonstrates the feasibility of pyrolysis, which mainly includes pyrolysis characteristics, product properties, related problems, the prospects and future challenges of pyrolysis of medical wastes.
Показать больше [+] Меньше [-]Electrocatalytic inactivation of antibiotic resistant bacteria and control of antibiotic resistance dissemination risk
2021
Liu, Haiyang | Hua, Xiuyi | Zhang, Ya-nan | Zhang, Tingting | Qu, Jiao | Nolte, Tom M. | Chen, Guangchao | Dong, Deming
Antibiotic resistance in environmental matrices becomes urgently significant for public health and has been considered as an emerging environmental contaminant. In this work, the ampicillin-resistant Escherichia coli (AR E. coli) and corresponding resistance genes (blaTEM₋₁) were effectively eliminated by the electrocatalytic process, and the dissemination risk of antibiotic resistance was also investigated. All the AR E. coli (∼8 log) was inactivated and 8.17 log blaTEM₋₁ was degraded by the carbon nanotubes/agarose/titanium (CNTs/AG/Ti) electrode within 30 min. AR E. coli was inactivated mainly attributing to the damage of cell membrane, which was attacked by reactive oxygen species and subsequent leakage of intracellular cytoplasm. The blaTEM₋₁ was degraded owing to the strand breaking in the process of electrocatalytic degradation. Furthermore, the dissemination risk of antibiotic resistance was effectively controlled after being electrocatalytic treatment. This study provided an effective electrocatalytic technology for the inactivation of antibiotic resistant bacteria and control of antibiotic resistance dissemination risk in the aqueous environment.
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