China is the largest energy consumer and CO₂ emitter in the world. Industrial ecologicalization (IE) as an effective way to reduce carbon emission and achieve green growth is vital for China to strive to peak carbon dioxide emissions before 2030 and achieve carbon neutrality before 2060. Thus, it is necessary and urgent to evaluate the industrial ecologicalization level (IEL) in China. Based on the connotation and characteristics of IE and PSR model, this paper first establishes a comprehensive evaluation index system of the IEL and then uses the global entropy method (OEM) and spatial data analysis (ESDA) to analyze the dynamic evaluation, regional disparity, and spatial correlation of IEL in China. The results show that: (1) The innovation support and the structure optimization are the main stimulus in improving the IEL in China, whose weights of indexes have reached 0.263 and 0.268. (2) The overall IEL has improved steadily in China but differs significantly among provinces during the research period. (3) The regional disparity of IEL presents the Eastern region is leading, whereas the Middle and Western regions are lagging from a geographical perspective; the Northern Coast and Eastern Coast have ranked the top two compared with other six economic regions. (4) The five provinces, namely Beijing, Tianjin, Shanghai, Jiangsu, and Zhejiang, constitute the main agglomeration areas of IEL in China based on the spatial correlation features. The findings of this paper cannot only provide a theoretical basis and practice reference for IEL evaluation but also benefit more focused policy-making of the sustainable development in China.

The aim of this study was to evaluate deep sediment toxicity in Genoa submarine canyons (Northwestern Mediterranean), for the first time, by using an integrated approach that combined chemistry and ecotoxicology. Sediments were collected from the main submarine canyons in the Gulf of Genoa (Polcevera and Bisagno) and along the adjacent Western Open Slope. A multi-endpoint ecotoxicological approach was taken by exposing two crustacean larvae (Amphibalanus amphitrite and Artemia sp.). Lethal and sub-lethal responses (mortality, swimming behavior) were investigated. Chemical analysis showed that this area is characterized by metal enrichment, including lead, cadmium, chromium, and nickel. Ecotoxicological tests highlighted that elutriates from the different submarine canyons were toxic only for A. amphitrite nauplii: Polcevera Canyon and Western Open Slope sediments induced stronger lethal and sub-lethal ecotoxicological effects than those from Bisagno Canyon. No direct correlation was found between the outcome of chemical and ecotoxicological characterization. However, barnacle was the most prone species to metal contamination: lethal and sub-lethal responses found in this species may be linked to an increase in the concentration of some metals (i.e., Cr, Ni) from offshore to coastal waters, probably due to anthropogenic activity. These findings suggest that the proposed approach can be a suitable tool for deep-sea sediment contamination monitoring; however, the use of a battery of bioassays involving multiple species and endpoints is recommended to better clarify the dynamics of contaminants in marine sediments at very high depths.

Fisetin is a polyphenolic flavonoid reported to have antioxidant, anti-inflammatory, and anti-cancer activities. However, it loses its importance as an effective phytochemical due to its poor water solubility and lower bioavailability. In the present study, the self-nanoemulsifying drug delivery system (SNEDDS) of fisetin was developed in order to improve its pharmacological activity. The developed SNEDDS of fisetin was evaluated for improving the rotenone-induced behavioral changes in the rats, and its efficacy was compared with naïve fisetin. It was noticed that fisetin loaded in the SNEDDS formulation significantly (p < 0.001) ameliorated the rotenone-induced alteration in the body weight, grip strength, beam walk, postural instability, etc., in rats when compared to the effect of naïve fisetin. Naïve fisetin significantly (p < 0.05) ameliorated the effect of rotenone on the level of dopamine only at a higher dose. Whereas, SNEDDS of fisetin produced a significant (p < 0.05) effect at both dose levels when compared with the diseased group as well as also produced a significant (p < 0.05) effect when compared with the naïve fisetin group. The results of histopathological examination revealed about the neuroprotective effect of SNEDDS loaded with fisetin as observed through the protection of neuronal damage. From this study, it was concluded that SNEDDS improved the anti-Parkinsonian activity of fisetin by improving the behavioral alteration produced by rotenone due to enhancement in its solubility and bioavailability.

During zinc hydrometallurgy process, the chloride ions in the materials go into the leaching solution, which have abominable effects on equipment, electrowinning, and environment. So, it is necessary to remove chloride ions from zinc sulfate solution. The present review outlines the current research of removal methods of chlorine by holistically highlighting the advantages and mechanisms. The main techniques used to remove chloride ions from zinc sulfate solution are also discussed in detail. Among the methods, the precipitation method using copper slag to remove chlorine is widely used and the chlorine removal rate is up to 98%. In addition, the combination of electrochemistry and nanofiltration technology can form a closed-loop production process with less waste output and near-zero emissions. In addition, the challenges and possible future directions of chlorine removal from zinc sulfate solutions are also delineated.

The intensification of international trade movements and economic interconnectivity has far-reaching implications for many macroeconomic indicators, not to mention ecological consequences. To this end, this analysis examines the dynamic interaction between foreign direct investment (FDI), natural resources, economic advancement, and urbanization on consumption-based carbon emission which is adjusted to global trade for oil-producing Sub-Saharan Africa countries. The time frame for this analysis is from 1990 to 2018. To examine the nature of relationship between the outlined variables, a balanced panel econometric analysis alongside augmented mean group (AMG), common correlated effect mean group (CCEMG), and the Driscoll-Kraay(DK) OLS techniques while the system-GMM was utilized for robustness purposes. The outcomes reveal that income increases consumption-based carbon emission within the range of 0.668 to 1.1333%; natural resources also increase consumption-based carbon emission within the range of 0.0159 to 0.2304%; FDI on the other hand increases consumption-based carbon emission around 0.0156 to 0.186%, while urbanization increases consumption-based carbon emission within the range of 0.0231 to 0.6176% in the long run. Thus, there is a positive relationship between consumption-based carbon emission and all the understudied variables within the oil-producing Sub-Sahara Africa countries thereby affirming the pollutant haven hypothesis for the countries on the premises that foreign direct investment inflow has a detrimental influence on the receiving economies alongside natural resource. Hence, the outcomes suggest the need to pursue low-carbon strategies for a cleaner and friendly environment.

The evidence regarding the association between long-term fine particulate (PM₂.₅) exposure and cardiovascular disease (CVD) in developing countries is limited. This study investigated the association between long-term exposure to PM₂.₅ and the prevalence of CVD among middle-aged and older adults. A total of 13,484 adults ≥ 45 years of age were surveyed in China, and logistic regression models were used to examine the association between PM₂.₅ and the prevalence of CVD. Furthermore, stratified analyses were conducted to explore potential effect modifiers. In addition, the burden of CVD attributable to PM₂.₅ was estimated. The analyses revealed that PM₂.₅ was associated with CVD, with an adjusted odds ratio (OR) of 1.18 (95% confidence interval [CI]: 1.12, 1.26) for each 10 μg/m³ increment in ambient PM₂.₅. Stratified analyses found that the elderly may be a vulnerable population. It was further estimated that approximately 20.27% (95% CI: 11.86%, 29.96%) of CVD cases could be attributable to PM₂.₅. This nationwide study confirmed that long-term exposure to PM₂.₅ was associated with an increased prevalence of CVD in China.

Widespread contamination of the superficial, drinking, and groundwater by perfluoroalkyl substances (PFASs) was discovered in the Veneto Region (northeast of Italy) in 2013. Mothers from the contaminated area were concerned about the effects of PFAS on their own and their children’s health. We determined the factors that influenced the perceived risk of PFAS and the presence of self-reported diseases by conducting a study with 384 mothers of children aged 1–13 years living in the contaminated area (Red Zone, Veneto, Italy). Information on demography, the sources of exposure, and the health condition of the mothers was collected through an online survey. The serum PFAS concentration was recorded for some of the participants. We determined the factors influencing the perceived risk, risk of health outcomes, and serum PFAS levels through regression analyses. The PFAS perceived risk of the mothers increased with an increase in the trust in scientific institutions and social media, and when many friends were present, trust in politics and full-time employment had a protective effect. The PFAS perceived risk increased the occurrences of self-reported and autoimmune diseases. Longer residence (> 20 years) in the most exposed area (Red Zone A) increased the frequency of some health outcomes. Serum PFAS concentrations decreased with breastfeeding, but increased with tap water consumption, residence in Red Zone A, and residence time. The PFAS perceived risk of the mothers was associated with many factors that influenced reporting of health issues. The association between PFAS exposure and health outcomes needs further investigation.

The problem of low adsorption capacity of pristine magnetic biochar for organic pollutants always occurs. It is of great significance to select a suitable method to improve the adsorption performance of magnetic biochar. In this study, magnetic biochar was treated by ball milling and tested for its fluconazole adsorption capacity. The maximum adsorption capacity of ball-milled magnetic biochar (BMBC) for fluconazole reached nearly 15.90 mg/g, which was approximately five times higher than that of pristine magnetic biochar (MBC). Fluconazole adsorption by BMBC was mainly attributed to π–π interactions, hydrogen bonding, and surface complexation with oxygen-containing functional groups. The enhancement in fluconazole adsorption by BMBC was attributed to an increase in oxygen-containing functional groups. Batch adsorption experiments also illustrated that BMBC could be successfully applied in a wide range of pH values. The high efficiency of fluconazole removal confirmed that ball milling was an effective strategy to enhance the adsorptive performance of magnetic biochar.

Heavy metal (HM) pollution and the need to preserve the environment have gathered increasing scientific attention. The immobilization of HMs into less-soluble, less mobile, and less toxic forms in addition to the improvement of Medicago sativa L. growth and HMs accumulation were evaluated after the application of marble waste (MW) and/or beneficial PGP rhizobacteria and mycorrhizae to the mining soil compost. A greenhouse assay was conducted to elucidate the influence of both amendment and beneficial microorganisms. The application of marble waste to the soil-compost resulted in decreasing the bioavailability of metals (Cu, Zn, Pb, and Cd), thus ameliorating the installation of the vegetal cover for 6 months of culture. Cultivation of M. sativa under 5% MW-amended soil for 6 months increased the shoot dry weight by almost twofold, while the inoculation with rhizobacteria-mycorrhizae combined with the application of 15% MW resulted in an improvement of 3.5-fold in case of shoot dry weight. In addition, the application of marble waste amendment or their combination with metallo-resistant bacteria resulted in decreasing HM accumulation leading to HM content below the threshold recommended for animal grazing. Thus, the application of amendments and beneficial microorganisms appeared to guarantee the safe cultivation of alfalfa for 6 months of culture. The dual combination amendments and beneficial microorganisms showed the good potential to restore HM polluted soils and could stand as a novel approach for restoration of HM-contaminated soils.

This research aims to examine the impact of financial development and renewable energy consumption on CO₂ emissions in CEMAC for the period 1990–2018. The study employs spatial analysis approach. As previous investigations have overlooked the effects of the spatial interactions in demonstrating environmental sustainability across nations, this paper gives the first comprehensive spatial analysis of CO₂ emissions among countries. To eliminate possible bias and inefficiency in estimated coefficients, the spatial autoregressive model is used to account for both geographical dependency and individual heterogeneity. The results revealed that under economic distance weights, the values of the spatial lag coefficients of financial development (FD), foreign direct investment (FDI), gross domestic product (GDP), and renewable energy consumption depict negative and statistical significance effects regarding spatial fixed effects in the SDM model, while trade openness (TO) shows a negative and insignificant impact. Other decomposition effects results show that FD had both direct and indirect significantly negative effects on environmental sustainability in CEMAC. This indicates that FD has a significant negative effect on CO₂ emissions in both the local country and its adjoining countries. On average, a unit change in FD in each country and its neighboring countries would reduce dioxide carbon by 0.071 and 0.066, respectively, and that of the whole region would be 0.137 units, meaning that environmental sustainability will improve. However, GDP recorded significantly positive direct and indirect effects on environmental sustainability. The direct and indirect effects of FDI on CO2 in both the local and neighboring countries were negative but statistically insignificant. On the other hand, the direct and indirect effects of TO on environmental sustainability were positive and statistically significant. Along with significant and statistical effects of financial development, GDP, FDI, renewable energy consumption, and TO, the findings reveal the presence of a positive spatial dependency of CO₂ emissions in CEMAC. This implies that policymakers in CEMAC countries lean to rely on their environmental sustainability decisions to assign financial and investments to that of neighboring nations. Furthermore, the findings indicate that adjacent countries’ FD and REC have a considerable impact on a country’s CO₂ emissions. Our findings offer significant political implications, implying that financial development and renewable energy consumption should be strengthened to meet environmental sustainability goals.