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Результаты 4621-4630 из 8,010
Investigating the effects of occupational and environmental noise on cardiovascular diseases: a systematic review and meta-analysis Полный текст
2021
Rabiei, Hadiseh | Ramezanifar, Soleiman | Hassanipour, Soheil | Gharari, Noradin
The present study aimed to use a meta-analysis to investigate the relationship between occupational and non-occupational noise exposure expressed in various studies with cardiovascular disease. This is a systematic review and meta-analysis study based on PRISMA checklist. In this study, the researchers searched five international databases of Medline/PubMed, Embase, Scopus, ISI/web of knowledge, and Google Scholar. Search keywords included two categories noise and noise pollution, cardiovascular disease, and hypertension. The Joanna Briggs Institute checklist was used to review and control the quality of the articles. After all screening stage 139 articles entered the final analysis. The results show that except for East African environmental studies and workplace studies in East Asia, Western Asia, and Northern Europe, there was a significant association between noise exposure and cardiovascular disease. Also, there was a significant difference between the intensity of sound and blood pressure in workers (OR = 1.28, CI 95%: 1.15–1.42, P < 0.001). Based on the results of environmental noise, there was a significant difference between ambient noise intensity and blood pressure (OR = 1.55, CI 95%: 1.53–1.57, P < 0.001). It can be concluded that it is very important to study and identify jobs or living environments with less than the recommended noise level and in addition to hearing aids that occur in over-standard exposures, such as cardiovascular disease.
Показать больше [+] Меньше [-]Evaluation of the Carbon Nanostructures Toxicity as a Function of Their Dimensionality Using Model Organisms: a Review Полный текст
2021
da Rosa, Paulo Castro Cardoso | Leão, Mayara Bitencourt | Dalla Corte, Cristiane Lenz | de Matos, Carolina Ferreira
Nanotechnology has been widely used, with nanomaterials being applied in several technologies. However, little is known about the real toxicological risk that can be caused by nanomaterials. These materials can be divided according to their dimensionalities. The current classification schemes for nanostructured materials are based on these dimensionalities, generally as zero (0D), one (1D), two (2D), and three dimensions (3D). Toxicological studies to present broad and consistent information on nanomaterials toxicity mechanisms, in vitro and in vivo studies in several experimental models are necessary. Thus, this short review presents the toxicological potential of carbon nanomaterials, divided by their dimensionality, in the main in vitro and in vivo experimental models, especially alternative models. As a result, it was possible to observe that the toxicity of carbon nanomaterials does not vary according to the dimensionality of 0D, 1D, and 2D materials. For these materials, it is not possible to infer a direct relationship between dimensionality and toxicity. However, recent studies have shown that three-dimensional graphene species tend to have less toxicity than materials with a smaller number of dimensions. Finally, it was possible to note the importance of using several experimental models, especially alternative models, in order to increase the understanding of toxicity mechanisms of carbon nanomaterials.
Показать больше [+] Меньше [-]A novel assessment and forecasting system for traffic accident economic loss caused by air pollution Полный текст
2021
Wang, Jianzhou | Li, Hongmin | Wang, Ying | Yang, Hufang
Air pollution greatly reduces the visibility of the air, leading to frequent traffic accidents (TA), and the resulting economic losses cannot be ignored. In order to better control and mitigate the traffic accident economic losses of air pollution, this paper proposes a novel assessment and forecasting system for TA economic loss of air pollution, which contains assessment module and forecasting module. In the assessment module, a reasonable assessment of TA economic loss is provided which also analyzes the efficiency of air pollution control based on data envelope analysis directional distance function. In the forecasting module, this system develops a rolling nonlinear optimized initial self-adapting grey model based on multi-objective optimization algorithm to forecast the TA economic loss of air pollution. The results from the proposed system indicate that the proposed system has outstanding performance which can provide great information assistant for a decision-maker.
Показать больше [+] Меньше [-]Cytotoxic and genotoxic effects of clopyralid herbicide on Allium cepa roots Полный текст
2021
Amaç, Eslem | Liman, Recep
Clopyralid is one of the synthetic pyridine-carboxylate auxin herbicides and used to control perennial and annual broadleaf weeds in wheat, sugar beets, canola, etc. In this study, dose-dependent cytotoxicity and genotoxicity of clopyralid at different concentrations (25, 50, and 100 μg/mL) have been evaluated on the Allium cepa roots. The evaluation has been performed at macroscopic (root growth) and microscopic levels [mitotic index (MI), chromosome aberrations (CAs) in ana-telophase cells, and DNA damage] using root growth inhibition, Allium ana-telophase, and comet tests. The percentage of root growth inhibition and concentration of reducing root growth by 50% (EC₅₀) of clopyralid were determined compared with the negative control by using various concentrations of clopyralid (6.25–1000 μg/L). The 96 h EC₅₀ of clopyralid was recorded as 50 μg/L. The gradual decrease in root growth and the MI reveals the cytotoxic effects of clopyralid. All the tested concentrations of clopyralid induced total CAs (polyploidy, stickiness, anaphase bridges, chromosome laggards, and disturbed ana-telophase) and DNA damage dose and time dependently. These results confirm the cytotoxic and genotoxic effects of clopyralid on non-target organism.
Показать больше [+] Меньше [-]In vitro effects of erythromycin and florfenicol on primary cell lines of Unio crassus and Cyprinus carpio Полный текст
2021
Arslan, Pınar | Yurdakok-Dikmen, Begum | Ozeren, Saniye Cevher | Kuzukiran, Ozgur | Filazi, Ayhan
The ubiquitous use of antibiotics leads exposure of these chemicals on non-target aquatic species, while the toxicity assays for these chemicals are time/labor consuming and expensive. Alternative approaches using primary cell cultures which retain the tissue functionality at its highest form have received global attention compared to cell lines. In the current study, the cytotoxic effects of two commonly used antibiotics from amphenicol (florfenicol) and macrolide (erythromycin) groups were evaluated on primary cell cultures of Unio crassus (mantle, digestive gland, gill, and gonad) and Cyprinus carpio (gill and liver) using MTT and Neutral Red assays. The highest cytotoxic effects were found on the mussel digestive gland and carp liver cells for florfenicol and erythromycin, while the lowest cytotoxic effects were found in mussel mantle cells for both drugs in the MTT test. In the NR test, the highest cytotoxic effects of erythromycin and florfenicol were found in the mussel gill, mantle, gonad, and carp gill cells; the lowest cytotoxic effect of erythromycin was found in the mussel digestive gland, while the lowest effect of florfenicol was found in the carp liver cells. The cytotoxicity of florfenicol was quite low for the carp liver, while the cytotoxicity of erythromycin was quite low in the mussel digestive tract. Thus, it was concluded that cells made from mussel tissues could be used in ecotoxicity tests, and sensitivity may vary according to the tissue.
Показать больше [+] Меньше [-]Optimization of hybrid treatment of olive mill wastewaters through impregnation onto raw cypress sawdust and electrocoagulation Полный текст
2021
This research investigation proposes a new method for sustainable olive mill wastewater (OMW) treatment and handling. It is based on the combination of its impregnation onto raw cypress sawdust (RCS) followed by electrocoagulation. The retention of OMW compounds onto various RCS doses show an important decrease of its chemical oxygen demand (COD) and its main cation and anion content. The maximum retention efficiencies of COD, Na⁺, K⁺, Ca²⁺, Mg²⁺, Cl⁻, [Formula: see text], and [Formula: see text] were about 51.0%, 75.3%, 28.7%, 77.9%, 84.7%, 41.1%, 98.3%, and 90.9%, respectively, for the highest RCS dose (200 g L⁻¹). This organic matter- and nutrient-loaded biomass could be thermochemically converted through pyrolysis into biofuel and biochar for energetic and agronomic purposes, respectively. The treatment by electrocoagulation of the pre-treated OMW using mild steel electrodes could be considered an attractive treatment method since 75.6% of COD removal efficiency was achieved. Besides, this approach permits a significant energy consumption reduction by 46% as compared with the electrocoagulation process alone. It allows also a significant improvement of the treated effluent quality in terms of both organic and mineral contents that could be reused for the irrigation of olive trees in the context of circular economy.
Показать больше [+] Меньше [-]Re-evaluating the asymmetric conventional energy and renewable energy consumption-economic growth nexus for Pakistan Полный текст
2021
Jafri, Muhammad Afaq Haider | Liu, Huizheng | Usman, Ahmed | Khan, Qasim Raza
To understand the nexus between economic growth and energy sources, in this study, we have selected Pakistan and collected data over the period 1980–2016. The neoclassical production function of Pakistan is augmented with conventional and renewable energy, capital, and labor. Conversely, the conventional and renewable models are being constructed by using GDP as an independent variable. This paper applied linear and nonlinear ARDL models to see whether the influence of conventional and renewable energy consumption on GDP per capita of Pakistan is symmetric or asymmetric and vice versa. Furthermore, the asymmetric causal effects between the energy variables and economic growth are also discussed. From the findings of the study, we deduce the long-run asymmetric effects of renewable energy on the economic growth of Pakistan. Similarly, the asymmetric effects of GDP, in the long run, are confirmed in both energy models. The symmetric and asymmetric causality results have recommended growth and conservation hypothesis. The findings propose that renewable energy is a significant factor in boosting the economic growth of Pakistan and a decline in the use of renewable energy could actually stem the economic growth of Pakistan.
Показать больше [+] Меньше [-]Total organic carbon as a proxy for metal release from biostabilized wastes Полный текст
2021
Lieto, Alessio | Verginelli, Iason | Zingaretti, Daniela | Lombardi, Francesco
In this study, we introduce a simple screening method to predict the metal release from biostabilized wastes as a function of the total organic carbon (TOC) content of the sample. The method relies on a model that simulates the release of dissolved organic carbon (DOC) as a function of the applied liquid to solid (L/S) ratio. The metal release is then estimated using generic empirical DOC to metal correlation coefficients (KDOC,Mₑ) extrapolated from the literature. Specifically, the results of leaching tests carried out on different types of biowastes and biostabilized wastes were used to calculate the upper and lower KDOC,Mₑ values that can be expected for common metals of concern (Al, Ba, Cr, Cu, Mo, Ni, Pb, V, and Zn). The statistical analysis of the estimated empirical coefficients highlighted that for most of the investigated metals, the adoption of generic DOC to metal correlation coefficients introduces relatively low uncertainties. The quartiles ratio (QR calculated as the ratio of third and first quartile) of the KDOC,Mₑ coefficients extrapolated from the literature was indeed below 3 for Cu, Ni, and Zn and below 5 for Al, Ba, Cr, Pb, and V. Only for Mo, the QR was around 10 indicating that for this element, DOC can be a poor indicator of the release expected as a function of the applied L/S. Furthermore, by performing a sensitivity analysis, we found that the experimental conditions only slightly influence the metals release predicted by the model. Based on this evidence, simple nomograms that estimate the cumulative metal release in percolation column tests as a function of the applied L/S are provided. Furthermore, a simple equation that predicts the cumulative metal release expected at L/S of 10 L/kg is presented. The application of the latter to the results of percolation column tests carried out on 8 mechanical biological treatment (MBT) waste samples highlighted that the predicted metals release was close to the measured values with deviations within a factor of 5 for all the investigated metals.
Показать больше [+] Меньше [-]Is COVID-19 associated with latent toxoplasmosis? Полный текст
2021
The present study aimed to evaluate the possible association between coronavirus disease 2019 (COVID-19) and latent Toxoplasma gondii infection in a group of patients and healthy individuals. Blood samples were obtained from 269 PCR-positive COVID-19 patients. The serum was separated and tested for the existence of anti-T. gondii antibodies (IgG) using a commercial enzyme-linked immunosorbent assay kit. The prevalence of latent toxoplasmosis between a subgroup of the patients (aged under 55 years old) and COVID-19 negative individuals was compared. Anti-T. gondii antibodies were found in 226/269 (84.0%) patients with COVID-19. Anti-Toxoplasma antibodies were detected in 72/91 (79.1%) cases and 96/123 (78.0%) COVID-19 negative individuals (odd ratio = 1.1; 95% confidence interval: 0.55–2.07, P = 0.85). The median and interquartile range (IQR) of the IgG titer were not statistically significant different between case (97.3 [31.0–133.5]) and control groups (34.4 [13.0–144.5]) (P = 0.10). These findings demonstrated that latent Toxoplasma infection is prevalent amongst the COVID-19 patients. It also did not find any significant association between chronic toxoplasmosis and COVID-19.
Показать больше [+] Меньше [-]Contribution of Piriformospora indica on improving the nutritional quality of greenhouse tomato and its resistance against cu toxicity after humic acid addition to soil Полный текст
2021
Protected cultivation has a significant contribution in vegetable production. We investigated whether humic acid addition to soil and Piriformospora indica can improve the nutritional quality of greenhouse tomato. We conducted a pot experiment, in which the effects of P. indica inoculation, humic acid addition, and Cu spiking to soil (0, 120, 240, and 500 ppm Cu) were tested. Humic acid addition to soil spiked with 500 ppm Cu decreased the Cu concentration in the fruits of plants inoculated with P. indica from 0.65 to 0.40 mg 100 g Fw⁻¹, which is still above the maximum allowed limits of Cu in tomato by World Health Organization (WHO). The lycopene and ascorbic acid content of tomato fruits were consistently improved by humic acid addition and P. indica inoculation. The antioxidant enzymes’ activity changed in response to humic acid addition, Cu spiking to soil, and P. indica inoculation. With increasing Cu level up to 240 ppm, the activity of superoxide dismutase (SOD) and peroxidase (POD) increased significantly. However, with spiking more Cu to soil, the activity of antioxidant enzymes reduced and the MDA content increased significantly. Addition of humic acid to soil and/or presence of P. indica increased the activity of antioxidant enzymes when the soil spiked with 500 ppm Cu. This study indicated that addition of P. indica and humic acid to the soil can enhance the nutritional quality of greenhouse tomato by reduction of Cu toxicity as a common pollutant in the greenhouse media and increasing the antioxidant content of fruits.
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