Nowadays excessively used corticosteroids in veterinary medicine induce steroid hepatopathy in dogs (Canis lupus familiaris). The objective of this study was to determine the possibility of the hepatoprotectants to decrease the corticosteroid-induced alteration in such dogs’ blood serum enzymes as alaninaminotransferase (ALAT), gammaglutamyltranferase (GGT), alkaline phosphatase (AP) and corticosteroid-induced thermostable alkaline phosphatase (cAP). The study took place in private veterinary clinics in Riga, Latvia, during 2013, with the permission of dogs’ owners. Twenty eight animals, which received corticosteroids due to present diagnosis, were divided into two groups. In the first group long-lasting corticosteroid methylprednisolone acetate injection was used once, while in the second group the hepatoprotectants were used after the injection of corticosteroids. It was discovered that after 14 and after 30 days of hepatoprotectants use, blood enzymes were significantly lower (p is less than 0.05) than in dogs that did not receive hepatoprotectants. In both groups the enzyme values did not reach the reference limits. The study is set to investigate further if and when the values reach the reference limits.

The objective of the study was to examine how the circumstances of different bull daughters – Latvian Brown cow - group productivity levels correlate with the blood biochemical composition indices in Latvian conditions. The daughters of seven bulls, selected for our research trial, were kept in the same barn and under rearing conditions. Their blood samples were taken in a single sampling activity and analyzed for blood serum biochemical averages. Also Cu, Fe, Zn, Mn and Mg were detected in blood serum and the values found were compared with values fixed in regulatory documents. There were changes in Cu levels (daughter groups of four bulls), in Zn levels (one group); Mn level was lower in all groups and Mg level was higher in 6 groups. The altered biochemical parameters of blood were assessed from the pathogenetical point of view and compared with productivity averages in the progeny groups. The correlation factors suggested that there exist a strong positive correlation (p is less than 0.05) among a number of indicators, such as aspartate aminotransferase (ASAT) and protein r = 0.823; ASAT and somatic cell count (SCC), r = 0.737; blood protein and milk protein r = 0.903 - 0.917; albumins and protein r = 0.964; blood urea and milk protein r = 0.931 - 0.984 along with additional correlations. The correlation factors for the progeny group of each bull differed. The data obtained shows that the Latvian Brown cows crossed with other breeds produce cows with new genetic traits.

The changes in the serum immunoglobulins concentration were investigated in newborn heifers from birth to 7 days of age. The mothers of calves were determined serum and colostrum immunoglobulins (Ig) concentration. The research was carried out at the Latvia University of Agriculture (LLU), in dairy farm ''Ligotnes'' of the Research and Study Farm ''Vecauce'', in a loose housing system with 530 cows, of which 430 were milking cows. The cows during the dry period were kept tethered in the farm. Eighteen heifers and their dams (Latvian Brown and Holstein breeds) which calved from 30 November 2010 to 23 January 2011 were used in this study. The calves' serum total immunoglobulin concentration at birth was 9.0 ±1.31 mg dLE-1 (or 0.09 mg mLE-1), and after 24 hours (h) it increased significantly to 4.3 mg dLE-1 (or 0.043 mg mLE-1), p is less than 0.05. The immunoglobulin G (IgG) concentration in calf serum after birth was 6.8 ±1.50 mg dLE-1 (or 0.068 mg mLE-1), and after 1 day and after 7 days it did not change significantly. The average Ig serum concentration in cows was 12.6 ± 1.36 mg dLE-1(or 0.126 mg mLE-1), and Ig concentration in colostrum was 18.5 ± 1.68 mg mLE-1. On average, close correlation (r=0.56) was found between cow blood serum IgM and colostrum IgM. Correlation between cow and calf IgG serum concentration proved to be weak (r=0.49).

Avian metapneumovirus (AMPV), formerly known as avian pneumovirus (APV) is epizootic agent of turkey rhinotracheitis (TRT) and swollen head syndrome (SHS) in turkeys and chickens. The infection primarily affects the upper respiratory tract of young birds (broilers), while also decreases egg production of adult hens. Thus, the development of infection in susceptible birds of any age can cause serious economic losses. The purpose of this study is to test serums from broilers and hens for the presence of antibodies against the avian metapneumovirus. In this series of studies 317 serum samples taken from one 1 day to 75 weeks old birds were tested. Thus, on the basis of serological tests of blood serum and of chicken flocks and broilers, we had a preliminary diagnosis on the presence of avian metapneumovirus infection. Serological studies of unvaccinated against avian metapneumovirus infection bird flocks using the ELISA method showed antibody titers on average at 22 859 ± 4133. Avian metapneumovirus infection in birds was accompanied by a decrease in egg production of chicken flocks by 8.0 - 12.8%.

Corticosteroid therapy is often used on dogs (Canis lupus familiaris) to treat different kinds of diseases. One of the most common complications of corticosteroid use is steroid hepatopathy, a specific pathology only in dogs. The objective of this study was to determine whether and how significant the liver functional changes after one administration of different kinds of corticosteroids in standard dosages are. The study took place in private veterinary clinics in Riga, Latvia, during 2013 - 2014, with the permission of dogs’ owners. Twenty animals, which received corticosteroids due to present diagnosis, were divided into four groups. To reach the aim such corticosteroids as dexamethasone sodium phosphate, prednisolone acetate, methylprednisolone acetate and hydrocortisone aceponate were used in standard dosage one time to these dogs, respectively. Then, such blood serum enzymes as alaninaminotransferase (ALAT) and alkaline phosphatase (AP) were determined 24, 48 and 96 hours after the use of corticosteroids. It was discovered that the only one administration of dexamethasone sodium phosphate and methylprednisolone acetate in standard dosage can significantly increase (p is less than 0.05) ALAT and AP mean values in dogs. The corticosteroid prednisolone acetate was used once in standard dosage and hydrocortisone aceponate spray was used once and did not statistically significantly (p is greater than 0.05) change the values of alaninaminotransferase (ALAT) and alkaline phosphatase (AP) in dogs’ blood serum during this study.