The aim of this pilot study was to assess whether a single mesenchymal stem cell intra-articular injection in the osteoarthritic joint gives a therapeutic effect. This trial study was made in order to better manage and structure further study on more dogs. Single injections of 3 million mesenchymal stem cell intra-articular injections were made bilaterally in the osteoarthritic elbow joints. The dog was examined before and after monthly stem cell therapy using stance analyser scales to determine the static weight of each limb. Weight balance between forelegs improved, but not significantly (p is greater than 0.05). A radiographic examination was made for both elbow joints before stem cell therapy and the second and fifth month thereafter. Calculations of sub-trochlear sclerosis in percentage were made using mediolateral projections. Sub-trochlear sclerosis in percentage significantly decreased (p is less than 0.05) after stem cell therapy in both legs.

The aim of this study was to detect radiodensity of a medial coronoid process of elbow joints with a medial coronoid disease and normal elbow joints in dogs. The study includes 91 large and giant breed dogs at the age from 6 to 30 months. Medial coronoid disease was diagnosed in 65 dogs and 26 dogs had normal elbow joints. Computed tomography was performed with Philips MX – 16 CT scanner and imaging data analysis performed using Horos v.2.2.0 software. CT technical data included 140 kVp, 250 mAs, 1 second rotation time and 0.75 slice thickness. The density of a medial coronoid process (MCP) was measured by two unrelated measurement methods. The study describes Hounsfield unit values in different areas of MCP in normal elbow joints and in medial coronoid disease affected joints. In 91.8% cases, MCP subchondral sclerosis observed with MCP fragmentation or fissure. We conclude that both bone density measurement methods are suitable for veterinary diagnostic imaging and can be used to evaluate canine elbow joints.