At Banganga, Kapilbastu, Nepal, a field experiment was conducted in the spring of 2021 to determine the performances of transplanted spring rice under different weed management techniques. With five treatments and four replications, the experiment was structured as a single-factorial Randomized Complete Block Design (RCBD). The treatments consisted of Pretilachlor 50% EC (dose: 500 ml a.i. per acre) as pre-emergence herbicide, Pretilachlor 50% EC (dose: 500 ml a.i. per acre) as pre-emergence herbicide plus hand weeding at 20, 40 DAT, Hand weeding at 20 DAT, 40 DAT, 60 DAT, Cono-weeding at 20 DAT, 40 DAT, 60 DAT and control. The plots treated with Pretilachlor plus hand weeding recorded a significantly higher plant height (99cm), higher number of effective tillers per meter square (11.97), higher panicle length (26cm), and higher number of grains per panicle (200.60) at 90 DAT. The sterility percentage and the no. of grains per panicle were not affected by the weed management practices. Cono-weeding was found statistically superior in terms of grain yield (6.09 Mt ha-1) and harvest index (42.10 %). The experiment concluded that the weed management practices affect the grain yield of transplanted spring rice.