The study aimed to develop a methodology for determining zones of intra-field heterogeneity for precision farming. In this study, we took into account the Belarussian national land use system which provides for the absence of private ownership of agricultural land. The spatial distribution of intra-field heterogeneity zones within the land use area of 7549.49 thousand hectares was identified using the analytical hierarchy process (AHP). The algorithm for determining zones of spatial heterogeneity provides for: (1) the selection of indicators and their ranking; (2) developing a pairwise comparison matrix, (3) estimating relative weights and (4) assessing matrix consistency. It is recommended to use data from agrochemical soil studies which are conducted centrally every 4 years for each agricultural enterprise as input parameters. These data include the humus content in the soil, the content of available phosphorus and potassium, soil pH, and the content of B, Cu, Zn, Ca, and Mg. The data should be carefully examined using spatial statistics tools to provide a more accurate delineation of the management-zones boundaries. The developed technique makes it possible to determine fertile and marginal areas within each field and differentiate the use of fertilizers, taking into account the presence of intra-field heterogeneity. This will reduce the total cost of purchasing and applying phosphorus fertilizers by 34 $·haE−1 and potash fertilizers by 9 $·haE−1 due to the redistribution of the fertilizer dose calculated for the planned yield, taking into account the identified site-specific management zones. At the same time, the level of chemical pressure per hectare of arable land will decrease by 6.7% without loss of crops productivity.