The proliferation of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka may be attributed to exposure to trace elements of both natural and human origin in the environment, which has been extensively explored and widely debated within the scientific community. This research aims to investigate the fluctuation of soil quality in paddy fields concerning depth and to evaluate the corresponding groundwater parameters in a region identified as a high-risk area for CKDu in the North Central region via determining different parameters including trace metals in both paddy soils and groundwater. The slightly alkaline paddy soils in the study area displayed elevated electrical conductivity values in the uppermost soil layer compared to the subsoil layer. Although hazardous metals, including lead (Pb), chromium (Cr), arsenic (As), and cadmium (Cd), were detected in the paddy soil, they did not surpass the critical toxic concentrations. A statistically remarkable robust positive correlation was discovered between the concentration of Pb in the soil and its depth. Additionally, the levels of toxic metals, such as lead, arsenic, cadmium, and chromium, in the study area’s groundwater were substantially lower than the safety standards set by the World Health Organization. However, some groundwater samples were found to contain anionic species, including fluoride, in concentrations that exceeded the established permissible limits. The gradual accretion of trace elements within the paddy soil presents a potential hazard for the translocation of such elements into the rice plants, thus constituting a possible threat to human health.

Pesticides have been used for a long time in agriculture to prevent the growth of undesired organisms. However, depending on the type of production (i.e., conventional, organic, and regenerative), they might not be applied. Adequate types and uses of pesticides should not cause any damage to any non-target species or environments due to the exposure to it, especially if all farming operations have been done properly. Reversely, when pesticides are applied in inappropriate time, amount or technique, they may cause several impacts, among which is water contamination. Brazil stands out worldwide for its agricultural potential, but it is exposed to risks concerning the water supply security to its population. The current study is a comparison of the Maximum Permissible Concentrations (MPC) for pesticides in potable water supply in Brazil with the values set in the United States, Canada, European Union countries, Japan, and the guidelines issued by the World Health Organization. The regulations of each country were used, as well as the trading, consumption and agricultural production data. The Brazilian regulation is the one accounting for the largest number of pesticides. However, their MPC is 5,000 times more permissible than that from the European Union for the herbicide known as glyphosate, 300 times than that for 2,4-d and 20 times than that for atrazine. Finally, it was possible to observe the relevance of revising the regulation and public policies in place to minimize the indiscriminate use of pesticides in Brazil and adapt these compounds to the standards in a global level.