MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration Полный текст

2025

Zdouc, Mitja M | Blin, Kai | Louwen, Nico L | Navarro, Jorge | Loureiro, Catarina | Bader, Chantal D | Bailey, Constance B | Barra, Lena | Booth, Thomas J | Bozhüyük, Kenan A | Cediel-Becerra, José D | Charlop-Powers, Zachary | Chevrette, Marc G | Chooi, Yit Heng | D’agostino, Paul M | de Rond, Tristan | del Pup, Elena | Duncan, Katherine R | Gu, Wenjia | Hanif, Novriyandi | Helfrich, Eric J | Jenner, Matthew | Katsuyama, Yohei | Korenskaia, Aleksandra | Krug, Daniel | Libis, Vincent | Lund, George A | Mantri, Shrikant | Morgan, Kalindi D | Owen, Charlotte | Phan, Chin-Soon | Philmus, Benjamin | Reitz, Zachary L | Robinson, Serina L | Singh, Kumar Saurabh | Teufel, Robin | Tong, Yaojun | Tugizimana, Fidele | Ulanova, Dana | Winter, Jaclyn M | Aguilar, César | Akiyama, Daniel Y | Al-Salihi, Suhad A | Alanjary, Mohammad | Alberti, Fabrizio | Aleti, Gajender | Alharthi, Shumukh A | Rojo, Mariela y Arias | Arishi, Amr A | Augustijn, Hannah E | Avalon, Nicole E | Avelar-Rivas, J Abraham | Axt, Kyle K | Barbieri, Hellen B | Barbosa, Julio Cesar J | Barboza Segato, Lucas Gabriel | Barrett, Susanna E | Baunach, Martin | Beemelmanns, Christine | Beqaj, Dardan | Berger, Tim | Bernaldo-Agüero, Jordan | Bettenbühl, Sandra M | Bielinski, Vincent A | Biermann, Friederike | Borges, Ricardo M | Borriss, Rainer | Breitenbach, Milena | Bretscher, Kevin M | Brigham, Michael W | Buedenbender, Larissa | Bulcock, Brodie W | Cano-Prieto, Carolina | Capela, João | Carrion, Victor J | Carter, Riley S | Castelo-Branco, Raquel | Castro-Falcón, Gabriel | Chagas, Fernanda O | Charria-Girón, Esteban | Chaudhri, Ayesha Ahmed | Chaudhry, Vasvi | Choi, Hyukjae | Choi, Yukyung | Choupannejad, Roya | Chromy, Jakub | Donahey, Melinda S Chue | Collemare, Jérôme | Connolly, Jack A | Creamer, Kaitlin E | Crüsemann, Max | Cruz, Andres Arredondo | Cumsille, Andres | Dallery, Jean-Felix | Damas-Ramos, Luis Caleb | Damiani, Tito | de Kruijff, Martinus | Martín, Belén Delgado | Sala, Gerardo Della | Dillen, Jelle | Doering, Drew T | Dommaraju, Shravan R | Durusu, Suhan | Egbert, Susan | Ellerhorst, Mark | Faussurier, Baptiste | Fetter, Artem | Feuermann, Marc | Fewer, David P | Foldi, Jonathan | Frediansyah, Andri | Garza, Erin A | Gavriilidou, Athina | Gentile, Andrea | Gerke, Jennifer | Gerstmans, Hans | Gomez-Escribano, Juan Pablo | González-Salazar, Luz A | Grayson, Natalie E | Greco, Claudio | Gomez, Juan E Gris | Guerra, Sebastian | Flores, Shaday Guerrero | Gurevich, Alexey | Gutiérrez-García, Karina | Hart, Lauren | Haslinger, Kristina | He, Beibei | Hebra, Teo | Hemmann, Jethro L | Hindra, Hindra | Höing, Lars | Holland, Darren C | Holme, Jonathan E | Horch, Therese | Hrab, Pavlo | Hu, Jie | Huynh, Thanh-Hau | Hwang, Ji-Yeon | Iacovelli, Riccardo | Iftime, Dumitrita | Iorio, Marianna | Jayachandran, Sidharth | Jeong, Eunah | Jing, Jiayi | Jung, Jung J | Kakumu, Yuya | Kalkreuter, Edward | Kang, Kyo Bin | Kang, Sangwook | Kim, Wonyong | Kim, Geum Jin | Kim, Hyunwoo | Kim, Hyun Uk | Klapper, Martin | Koetsier, Robert A | Kollten, Cassandra | Kovács, Ákos T | Kriukova, Yelyzaveta | Kubach, Noel | Kunjapur, Aditya M | Kushnareva, Aleksandra K | Kust, Andreja | Lamber, Jessica | Larralde, Martin | Larsen, Niels J | Launay, Adrien P | Le, Ngoc-Thao-Hien | Lebeer, Sarah | Lee, Byung Tae | Lee, Kyungha | Lev, Katherine L | Li, Shu-Ming | Li, Yong-Xin | Licona-Cassani, Cuauhtémoc | Lien, Annette | Liu, Jing | Lopez, Julius Adam V | Machushynets, Nataliia V | Macias, Marla I | Mahmud, Taifo | Maleckis, Matiss | Martinez-Martinez, Añadir Maharai | Mast, Yvonne | Maximo, Marina F | Mcbride, Christina M | Mclellan, Rose M | Bhatt, Khyati Mehta | Melkonian, Chrats | Merrild, Aske | Metsä-Ketelä, Mikko | Mitchell, Douglas A | Müller, Alison V | Nguyen, Giang-Son | Nguyen, Hera T | Niedermeyer, Timo H J | O’hare, Julia H | Ossowicki, Adam | Ostash, Bohdan O | Otani, Hiroshi | Padva, Leo | Paliyal, Sunaina | Pan, Xinya | Panghal, Mohit | Parade, Dana | Park, Jiyoon | Parra, Jonathan | Rubio, Marcos Pedraza | Pham, Huong T | Pidot, Sacha J | Piel, Jörn | Pourmohsenin, Bita | Rakhmanov, Malik | Ramesh, Sangeetha | Rasmussen, Michelle H | Rego, Adriana | Reher, Raphael | Rice, Andrew J | Rigolet, Augustin | Romero-Otero, Adriana | Rosas-Becerra, Luis Rodrigo | Rosiles, Pablo Y | Rutz, Adriano | Ryu, Byeol | Sahadeo, Libby-Ann | Saldanha, Murrel | Salvi, Luca | Sánchez-Carvajal, Eduardo | Santos-Medellin, Christian | Sbaraini, Nicolau | Schoellhorn, Sydney M | Schumm, Clemens | Sehnal, Ludek | Selem, Nelly | Shah, Anjali D | Shishido, Tania K | Sieber, Simon | Silviani, Velina | Singh, Garima | Singh, Hemant | Sokolova, Nika | Sonnenschein, Eva C | Sosio, Margherita | Sowa, Sven T | Steffen, Karin | Stegmann, Evi | Streiff, Alena B | Strüder, Alena | Surup, Frank | Svenningsen, Tiziana | Sweeney, Douglas | Szenei, Judit | Tagirdzhanov, Azat | Tan, Bin | Tarnowski, Matthew J | Terlouw, Barbara R | Rey, Thomas | Thome, Nicola U | Torres Ortega, Laura Rosina | Tørring, Thomas | Trindade, Marla | Truman, Andrew W | Tvilum, Marie | Udwary, Daniel W | Ulbricht, Christoph | Vader, Lisa | van Wezel, Gilles P | Walmsley, Max | Warnasinghe, Randika | Weddeling, Heiner G | Weir, Angus N | Williams, Katherine | Williams, Sam E | Witte, Thomas E | Rocca, Steffaney M Wood | Yamada, Keith | Yang, Dong | Yang, Dongsoo | Yu, Jingwei | Zhou, Zhenyi | Ziemert, Nadine | Zimmer, Lukas | Zimmermann, Alina | Zimmermann, Christian | van der Hooft, Justin J | Linington, Roger G | Weber, Tilmann | Medema, Marnix H | Wageningen University and Research [Wageningen] (WUR) | Novo Nordisk Foundation Center for Biosustainability ; Danmarks Tekniske Universitet = Technical University of Denmark (DTU) | Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) | UNSW School of Chemistry [Sydney] ; University of New South Wales [Sydney] (UNSW) | Univ Konstanz, Dept. Chemistry ; University of Konstanz | Myria Biosciences AG | Dept. Microbiology and Cell Science, University of Florida | Ginkgo Bioworks [Boston, MA, États-Unis] | University of Florida Genetics Institute (UFGI) ; University of Florida [Gainesville] (UF) | School of Molecular Sciences, The University of Western Australia, Perth 6009, Australia | Chair of Technical Biochemistry, Technical Université of Dresden | School of Chemical Sciences [Auckland] ; University of Auckland [Auckland] | Biosciences Institute, Faculty of Medical Sciences [Newcastle] ; Newcastle University [Newcastle] | Sutro Biopharma, South San Francisco | Bogor Agricultural University (IPB) | Goethe University Frankfurt | LOEWE Centre for Translational Biodiversity Genomics (LOEWE-TBG) ; Partenaires INRAE | Senckenberg Society for Nature Research | Department of Chemistry [University of Warwick] ; University of Warwick [Coventry] | Warwick Integrative Synthetic Biology Centre (WISB) | Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo | Collaborative Research institute for Innovative Microbiology, University of Tokyo | Translational Genome Mining for Natural Products, University of Tübingen | Universität des Saarlandes [Saarbrücken] = Saarland University [Saarbrücken] | Helmholtz Centre for Infection Research (HZI) | Université Paris Cité (UPCité) | Generare Bioscience [Paris] | Rothamsted Research - Department of Soil Science, Harpenden, Royaume Uni ; Université Paris Diderot - Paris 7 (UPD7) | computational biology lab, National Agri-food and Biomanufacturing Institute, Punjab | Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad | University of Northern British Columbia [Prince George] (UNBC) | Department of Biochemistry and Metabolism, Department of Biochemistry and Metabolism, John Innes Centre, Norwich NR4 7UH, United Kingdom | Latvian Institute of Organic Synthesis [Riga, Lituania] | Department of Pharmaceutical Sciences, Oregon State University | Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara | Department of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology | Plant-Microbe Interactions, Institute of Environmental Biologyutrecht | University of Exeter | Université de Bâle = University of Basel = Basel Universität (Unibas) | State Key Laboratory of Microbial Metabolism ; Shanghai Jiao Tong University [Shanghai] | Department of Biochemistry, University of Johannesburg | Omnia Nutriology, Sandton | Department of Marine Resource Science, Faculty of Agriculture and Marine Science, Kochi University | Center for Advanced Marine Core Research ; Kochi University | Department of pharmacology and toxicology, University of Utah | Industrial Genomics Laboratory, FEMSA, México | Purdue University [West Lafayette] | Institute of Chemistry, UNICAMP | Department of Applied Sciences, University of Technology, Baghdad | School of Life Sciences [Warwick] ; University of Warwick [Coventry] | Department of Food and Animal Sciences, Tennessee State University | Swansea University | Escuela Nacional de Estudios Superiores Unidad Léon, Mexico | Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia | Institute Biology Leiden (IBL) ; Universiteit Leiden = Leiden University | Center for Marine Biotechnology and Biomedicine ; University of California (UC) | Instituto Politecnico Nacional [Mexico] (IPN) | Department of Chemistry, University of Manitoba | Department of Chemistry, University of Illinois Urbana-Champaign | Carl R. Woese Institute of Genomic Biology ; University of Illinois at Urbana-Champaign [Urbana] (UIUC) ; University of Illinois System-University of Illinois System | Universität Bonn = University of Bonn | Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine ; Eberhard Karls Universität Tübingen = University of Tübingen | Institute of Pharmaceutical Biology and Biotechnology, University of Marburg | Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico | Universidad Nacional Mayor de San Marcos (UNMSM) | Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] (UFRJ) | Instituto de Pesquisas de Produtos Naturais Walter Mors, Universidade Federal do Rio de Janeiro | Humboldt-Universität zu Berlin = Humboldt University of Berlin = Université Humboldt de Berlin (HU Berlin) | Universität Greifswald = University of Greifswald | Department of Crop Protection, Instituto de Hortofructicultura Subtropical y Mediterránea, Málaga | Department of Microbial Ecology, NIOO-KNAW | University of Leeds | Centro Interdisciplinar de Química e Bioloxía, Universidade de Coruña | Centre of Biological Engineering, University of Minho | Universidad de Málaga [Málaga] = University of Málaga [Málaga] | Centro Interdisciplinar de Investigação Marinha e Ambiental = Interdisciplinary Centre of Marine and Environmental Research [Matosinhos, Portugal] (CIIMAR) ; Universidade do Porto = University of Porto | Institute of Microbiology, Technical University of Braunschweig ; Institute of Microbiology, Technical University of Braunschweig | Zentrum für Molekularbiologie der Pflanzen (ZMBP) ; Eberhard Karls Universität Tübingen = University of Tübingen | Yeungnam University [South Korea] | Research Institute of Cell Culture, Yeungnam University | College of Pharmacy and Drug Information Research Institute, Sookmyung Women’s University | Fungal Natural Products, Westerdijk Fungal Biodiversity Institute | Manchester Institute of Biotechnology ; University of Manchester [Manchester] | Innovative Genomics Institute ; Partenaires INRAE | Department of Earth and Planetary Science [UC Berkeley] (EPS) ; University of California [Berkeley] (UC Berkeley) ; University of California (UC)-University of California (UC) | BIOlogie et GEstion des Risques en agriculture (BIOGER) ; Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB / CAS) ; Czech Academy of Sciences [Prague] (CAS) | Stazione Zoologica Anton Dohrn (SZN) | Department of Biosciences Engineering, University of Antwerp ; University of Antwerp (UA) | US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA | Biochemistry of Microorganisms, Faculty of Life Sciences: Food, Nutrition, and Health, University of Bayreuth, Kulmbach | Swiss Institute of Bioinformatics [Genève] (SIB) | Department of Applied Chemistry and Microbiology [Helsinki] ; Helsingin yliopisto = Helsingfors universitet = University of Helsinki | Research Center for Food Technology and Processing, National Research and Innovation Agency, Indonesia | National Research and Innovation Agency (BRIN) | J. Craig Venter Institute [La Jolla, USA] (JCVI) | NAICONS Srl, viale Ortles 22/4, Milan | Department of Chemistry, University of Parma | Leibniz Universität Hannover = Leibniz University Hannover | VIB-KU Leuven Center for Microbiology [Leuven, Belgium] ; Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven) | Department of Biology, Laboratory for Biomolecular Discovery & Engineering, KU Leuven | Department of Biosystems (BIOSYST) ; Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven) | Leibniz-Institut Deutsche Sammlung von Mikroorganismen und Zelllkulturen GmBH - DSMZ (GERMANY) ; Leibniz-Institut Deutsche Sammlung von Mikroorganismen und Zelllkulturen GmBH - DSMZ (GERMANY) | Instituto de Matematicas (UNAM) ; Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM) | Carnegie Institution for Science | Interdepartmental Program in Chemical Biology, University of Michigan | Life Sciences Institute [Ann Arbor, MI, USA] ; University of Michigan [Ann Arbor] ; University of Michigan System-University of Michigan System | University of Groningen [Groningen] | Department of Chemistry, The University of Hong Kong ; The University of Hong Kong (HKU) | Leibniz Institute for Natural Product Research and Infection Biology (Hans Knoell Institute) | Institute of Infectious Disease Research, McMaster University, Ontario | McMaster University Hamilton - Department of Biology | SINTEF Industry | Microbiology Group, Wageningen University & Research | Corteva agriscience | Natural Products Research Institute, College of Pharmacy, Seoul National University | Center for Cancer Research, National Cancer Institute, Maryland | VTT Technical Research Centre of Finland (VTT) | Department of Chemistry and Biochemistry, Florida State University, Chieftain Way, Tallahassee, Florida, USA (DCB) | Department of Applied Biology, College of Agricultural and Life Sciences, Chonnam National University, Gwangju | Department of Pharmacology, College of Medicine, Dongguk University | College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University | Department of Biological Sciences, KAIST, Daejeon | Department of Paleobiotechnology, Hans Knöll Institute, Jena | DTU Bioengineering ; Department of Biotechnology and Biomedicine ; Danmarks Tekniske Universitet = Technical University of Denmark (DTU)-Danmarks Tekniske Universitet = Technical University of Denmark (DTU) | Department of Chemical and Biomolecular Engineering, University of Delaware ; University of Delaware [Newark] | German Center for Infection Research - partner site Hannover-Braunschweig (DZIF) | Leiden University Medical Center (LUMC) ; Universiteit Leiden = Leiden University | Endogenomiks, Querétaro, Mexico | U-MaMi Centre of Excellence, Antwerp | Integrative Biology Research Unit, The Institute of Obesity Research, México | School of innovation and Sustainability,De La Salle University, Laguna | Department of Chemistry, De La Salle University, Manila | University of Strathclyde [Glasgow] | Department of Biotechnology and Biomedicine ; Danmarks Tekniske Universitet = Technical University of Denmark (DTU) | Technical University of Braunschweig, Institute of Microbiology | The Ferrier Research Institute ; Victoria University of Wellington | Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand. | Department of Biology, Faculty of Sciences, Utrecht University | Department of Biological and Chemical Engineering, Aarhus University | University of Turku | Freie Universität Berlin | Ivan Franko National University of Lviv | German-Ukrainian Core of Excellence in Natural Products Research, Lviv | Environmental Genomics and Systems Biology Division [LBNL Berkeley] (EGSB) ; Lawrence Berkeley National Laboratory [Berkeley] (LBNL) | Centro de Investigaciones en Productos Naturales, Universidad de Costa Rica (CIPRONA) | Centro Nacional de Innovaciones Biotecnologicas (Cenibiot) ; National Center of High Technology (CeNAT-CONARE) | Instituto de Investigaciones Farmacéuticas, Universidad de Costa Rica (INIFAR) | Doherty Institute, University of Melbourne | Institute of Microbiology [Zurich] ; Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich) | Department of Plant Pathology [Davis] ; University of California [Davis] (UC Davis) ; University of California (UC)-University of California (UC) | Department of Chemistry [Aarhus] ; Aarhus University [Aarhus] | Institute for Molecular Systems Biology [ETH Zurich] (IMSB) ; Department of Biology [ETH Zürich] (D-BIOL) ; Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)-Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich) | Laboratorio de Microbiologia Molecular y Biotecnologia Ambiantal, Centro de Biotecnologia DAL, Universidad Tecnica Federico Santa Maria, Valparaiso | Department of Chemistry and BioDiscovery Institute, University of North Texas | Research Centre for Toxic Compounds in the Environment [Brno] (RECETOX / MUNI) ; Faculty of Science [Brno] (SCI / MUNI) ; Masaryk University [Brno] = Masarykova univerzita [Brno] = Université Masaryk [Brno] (MU / MUNI)-Masaryk University [Brno] = Masarykova univerzita [Brno] = Université Masaryk [Brno] (MU / MUNI) | School of Biological Sciences [Bristol] ; University of Bristol [Bristol] | University of Bristol [Bristol] | Helsinki Institute of Life Science (HiLIFE) ; Helsingin yliopisto = Helsingfors universitet = University of Helsinki | Universität Zürich [Zürich] = University of Zurich (UZH) | Università degli Studi di Padova = University of Padua (Unipd) | Department of Biological Sciences and Evolutionary Studies Initiative, Vanderbilt University | German Center for Infectious Research - partner site Tübingen [Tübingen, Allemagne] (DZIF) | Groupe De Sangosse | Laboratoire conjoint BioPlantProducts (LRSV-BPP) ; Groupe De Sangosse-Laboratoire de Recherche en Sciences Végétales (LRSV) ; Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT) | Department of Biology, Laboratory of Biomolecular Discovery & Engineering, KU Leuven | Institute for Microbial Biotechnology and Metagenomics [Cape Town, South Africa] (IMBM) ; University of the Western Cape (UWC) | Department of Molecular Microbiology John Innes Centre (JIC) ; John Innes Centre [Norwich] ; Biotechnology and Biological Sciences Research Council (BBSRC)-Biotechnology and Biological Sciences Research Council (BBSRC) | Rosalind Franklin Institute, Harwell Science and Innovation Campus, Oxford | School of Applied Sciences, University of the West of England, Bristol | University of Ottawa [Ottawa] | Natural Products Discovery Center, The Herbert Wertheim, Florida | Synthetic Biology and Enzyme Engineering Laboratory, Department of Chemical and Biological Engineering, Korea University, Seoul | Shenzhen University [Shenzhen] | College of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals | Institute of Chemical, Environmental and Biological Engineering ; Technische Universitat Wein | Department of Chemistry [Simon Fraser University] ([SFU.ca]) ; Faculty of Sciences [SFU.ca] ; Simon Fraser University = Université Simon Fraser (SFU.ca)-Simon Fraser University = Université Simon Fraser (SFU.ca) | ANR-24-CE20-7299,ShySM,Des métabolites spécialisés timides : Un rôle pour les effecteurs non-protéiques dans les interactions plante-champignon ?(2024) | ANR-17-EURE-0007,SPS-GSR,Ecole Universitaire de Recherche de Sciences des Plantes de Paris-Saclay(2017) | ANR-22-CE44-0011,UMISYN,Accéder aux substances naturelles microbiennes actives grâce à la biologie de synthèse(2022) | European Project: 101000392 ,MARBLES