Immunogenicity on inactivated infectious bovine rhinotracheitis (IBR) and parainfluenza type-3 (PI3) vaccine
1988
Heo, Y. | Kim, D.W. | Park, B.K. | Yoo, H.S. | Kim, Y.H. | Rhee, Y.O. | Park, J.M. | Sul, D.S. (Rural Development Administration, Anyang (Korea R.). Agricultural Veterinary Research Inst.)
In the purpose of preventing bovine respiratory diseases, an experimental combined vaccine containing inactivated bovine rhinotracheitis (IBR) virus and parainfluenza-3 (PI3) virus was prepared, and tested for its safety and immunogenicity in guinea pigs and calves. Immune responses of the vaccinated animals indicated that serum neutralizing antibody was detected from 2 weeks after inoculation, and then was increased significantly followed by booster vaccination at 4 weeks or by challenge at 6 weeks
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