Biological activity of the newly synthesized D-seco and D-homoestratriene derivatives in in vivo and in vitro experiments. [Doctoral dissertation] | Biološka aktivnost novosintetisanih D-seko- i D-homo-estratrienskih derivata u in vivo i in vitro uslovima. Doktorska disertacija
2010
Jovanović-Šanta, S.
Some new compounds, 16- and 17-substituted 16,17-secoestratriene derivatives, as well as D-homoestratriene derivatives, were synthesized, starting from 3-benzyloxy-17-hydroxy-16,17-secoestra-1,3,5 (10)-triene-16-nitrile. The newly synthesized compounds were tested for their in vivo estrogenic and antiestrogenic activity, in vitro antiaromatase activity, antioxidative activity by DPPH and TBA tests, as well as antiproliferative activity against MCF-7 ATCC, MDA-MB-231, HT-29 and MRC-5 cell lines.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
[S. Javanović-Šanta]
页码
156 p.
其它主题
Enfermedades glaindulas mamarias; Naoplasme; Exparimentation in vitro; Madicament; Experimentacian in vitro; Experimentacian in vivo; Exparimentation in vivo
语言
塞尔维亚
注释
Summaries (En, Sr)
73 graphs
15 tables
247 ref.
类型
Bibliography; Non-Conventional; Summary; Thesis
团体作者
Univerzitet u Novom Sadu, Novi Sad (Serbia). Prirodno-matematički fakultet
2011-07-15
AGRIS AP