Deletions of the endocytic components VPS28 and VPS32 in Candida albicans lead to echinocandin and azole hypersensitivity.

Cornet, Muriel; Gaillardin, Claude; Richard, Mathias L

Deletions of the endocytic components VPS28 and VPS32 in Candida albicans lead to echinocandin and azole hypersensitivity.

2006

Cornet, Muriel | Gaillardin, Claude | Richard, Mathias L

Vps28p and Vps32p act in both the endocytic and the pH signaling pathways in yeasts and are required for Candida albicans virulence. Here, we show that deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents.

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AGROVOC关键词

candida albicans gene expression regulation virulence

书目信息

其它主题

Mesh : vesicular transport proteins; Mesh : candida albicans; Fungal; Mesh : endocytosis; Mesh : peptides; Ph ambiant signalling; Mesh : azoles; Vesicular transport protein; Mesh : nuclear proteins; Vps28; Mesh : lipoproteins; Mesh : gene expression regulation; Mesh : microbial sensitivity tests; Cyclic; Mesh : fungal proteins; Mesh : gene deletion; Antifungal agent; Mesh : antifungal agents; Vps32

语言

英语

类型

Art

来源

American Society for Microbiology

自何时收录于AGRIS: 2021-03-15

格式: AGRIS AP

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这条记录提供自 Institut national de la recherche agronomique

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