Deletions of the endocytic components VPS28 and VPS32 in Candida albicans lead to echinocandin and azole hypersensitivity.

Cornet, Muriel; Gaillardin, Claude; Richard, Mathias L

Deletions of the endocytic components VPS28 and VPS32 in Candida albicans lead to echinocandin and azole hypersensitivity.

2006

Cornet, Muriel | Gaillardin, Claude | Richard, Mathias L

Vps28p and Vps32p act in both the endocytic and the pH signaling pathways in yeasts and are required for Candida albicans virulence. Here, we show that deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents.

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Ключевые слова АГРОВОК

candida albicans gene expression regulation virulence

Библиографическая информация

Другие темы

Mesh : vesicular transport proteins; Mesh : candida albicans; Fungal; Mesh : endocytosis; Mesh : peptides; Ph ambiant signalling; Mesh : azoles; Vesicular transport protein; Mesh : nuclear proteins; Vps28; Mesh : lipoproteins; Mesh : gene expression regulation; Mesh : microbial sensitivity tests; Cyclic; Mesh : fungal proteins; Mesh : gene deletion; Antifungal agent; Mesh : antifungal agents; Vps32

Язык

Английский

Тип

Art

Источник

American Society for Microbiology

В АГРИСе с: 2021-03-15

Формат: AGRIS AP

Поставщик данных

Эту запись предоставил Institut national de la recherche agronomique

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