Acetogenins from Annonaceae, inhibitors of mitochondrial complex I
1996
Zafra-Polo, M.C. | Gonzalez, M.C. | Estornell, E. | Sahpaz, S. | Cortes, D.
One-hundred and twenty-eight different linear, epoxy, mono-tetrahydrofuran, bis-tetrahydrofuran or tri-tetrahydrofuran acetogenins have been isolated from the Annonaceae. These new secondary metabolites are potent cytotoxic inhibitors of the mitochondrial NADH:ubiquinone oxidoreductase (complex I of the respiratory chain).
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书目信息
其它主题
Species specificity; Checklists; Medicinal; Derivatives; Isolation & purification; Ubiquinones; Nad (coenzyme); Molecular structure; Nad(p)h dehydrogenase (quinone); Molecular conformation; Antagonists & inhibitors; Chemical constituents of plants
语言
英语
注释
2019-12-05
类型
Journal Article; Text
2024-02-28
MODS