Inhibition of cAMP Phosphodiesterase by Some Phototherapeutic Agents
2014
Bovalini, Lucia | Lusini, Paola | Simoni, Sandra | Vedaldi, Daniela | Andreassi, Lucio | Dall’Acqua, Francesco | Martelli, Paola
The behaviour of cyclic-3′,5′-AMP phosphodiesterase has been studied in the presence of psoralen, 8-methoxy-psoralen (8-MOP), 4,5′,8-trimethylpsoralen (TMP) (usu ally used in PUVA therapy), 4.6,4′-trimethylangelicin (TMA) and khellin recently proposed for the same thera peutical use. TMP and TMA exhibit a significant inhibitory effect on cyclic AMP phosphodiesterase; a light inhibition is produced by khellin at rather high concentration.
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书目信息
Zeitschrift für Naturforschung
卷
42
期
7
页码
1009
- 1010
ISSN
1865-7125
出版者
Verlag der Zeitschrift für Naturforschung
其它主题
Phototherapy; Cyclic amp; Psoriasis; Furo-chromones; Cyclic amp phosphodiesterase; Psoralen; Puva therapy
语言
英语
类型
Journal Article; Text
2024-02-28
MODS