Diterpenoid compounds from Vitex agnus-castus
2013
Pal, Mahesh | Li, Sheng-Hong | Tewari, Shri Krishan | Sun, Han-Dong
A new diterpenoid alkaloid having an α,β-unsaturated γ-lactam moiety, 9α-hydroxy-13(14)-labden-16,15-amide (1), together with five known ones, was isolated from the fruits of Vitex angus-castus. The structure of 1 was elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques.The cytotoxicity of each compound was evaluated against human chronic myelogenous leukemia (K562) cell lines. Compound 1 was found to be the most potent with IC₅₀ value of 0.70 μg/mL.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
Springer-Verlag
其它主题
Diterpenoid alkaloids
语言
英语
类型
Journal Article; Text
2024-02-28
MODS