Cytotoxic flavonoids from the roots of Bougainvillea spectabilis
2021
Tran, Y B.N. | Nguyễn, Văn Kiêu | Nguyen, Phuong T.K.
Two new flavonoids, named bougainvinones N–O (1–2), together with the five known compounds (3–7), were isolated from the roots of Bougainvillea spectabilis. The chemical structures were elucidated by spectroscopic analyses, including 1D and 2D NMR and HR-ESI-MS. All compounds were evaluated for cytotoxic effects against four cancer cell lines, including HeLa, NCI-H460, MCF-7 and HepG2. Among them, bougainvinone O (2) showed moderate activity against the MCF-7 cell line, with an IC₅₀ value of 43.64 μM.
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书目信息
Phytochemistry letters
卷
42
页码
117
- 120
ISSN
1874-3900
出版者
Elsevier Ltd
其它主题
Bougainvinones; Neoplasm cells; Human cell lines
语言
英语
类型
Journal Article; Text
2024-02-28
MODS