Halogenation of Primary Alcohols Using a Tetraethylammonium Halide/[Et2NSF2]BF4 Combination

Pouliot, Marie-France; Mahé, Olivier; Hamel, Jean-Denys; Desroches, Justine; Paquin, Jean-François

Halogenation of Primary Alcohols Using a Tetraethylammonium Halide/[Et2NSF2]BF4 Combination

2012

Pouliot, Marie-France | Mahé, Olivier | Hamel, Jean-Denys | Desroches, Justine | Paquin, Jean-François

The halogenation of primary alcohols is presented. The use of a combination of tetraethylammonium halide and [Et₂NSF₂]BF₄ (XtalFluor-E) allows for chlorination and bromination reactions to proceed efficiently (up to 92% yield) with a wide range of alcohols. Iodination reactions are also possible albeit in lower yields.

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