A facile, environmentally benign sulfonamide synthesis in water

Tang, Siu-Fu; Mani, Neelakandha S.

A facile, environmentally benign sulfonamide synthesis in water

2006

Tang, Siu-Fu | Mani, Neelakandha S.

A facile, environmentally benign synthesis of sulfonamides under dynamic pH control in aqueous media is described. This methodology uses equimolar amounts of amino compounds and arylsulfonyl chlorides and omits the use of organic bases. Isolation of products involves only filtration after acidification. Excellent yields and purity were obtained without further purification.

显示更多 [+]